Results 251 to 260 of about 25,097 (300)
O uso de opioides nos cuidados paliativos oncológicos: Uma revisão de literatura
Vitória Rodrigues Franco da Rosa +3 more
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A EPIDEMIA SILENCIOSA: COMPREENDENDO A CRISE DE INTOXICAÇÃO POR OPIOIDES
William Roberto de Oliveira Rezende +3 more
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Opioides: cómo usarlos en el dolor persistente sin morir en el intento
Actualización en Medicina de Familia, 2023Puntos clave El consumo de opioides en España se ha incrementado en los últimos años como consecuencia de su utilización en el dolor persistente no oncológico (DPNO). La evidencia científica muestra que su uso en este tipo de dolor es poco eficaz y tiene
Aina Perelló Bratescu +1 more
semanticscholar +1 more source
Surgical Neurology, 2007
Opioids are the most effective and widely used drugs in the treatment of severe pain. They act through G protein-coupled receptors. Four families of endogenous ligands (opioid peptides) are known. The standard exogenous opioid analgesic is morphine. Opioid agonists can activate central and peripheral opioid receptors. Three classes of opioid receptors (
C, Zöllner, C, Stein
openaire +4 more sources
Opioids are the most effective and widely used drugs in the treatment of severe pain. They act through G protein-coupled receptors. Four families of endogenous ligands (opioid peptides) are known. The standard exogenous opioid analgesic is morphine. Opioid agonists can activate central and peripheral opioid receptors. Three classes of opioid receptors (
C, Zöllner, C, Stein
openaire +4 more sources
Opioid mechanisms and opioid drugs
Anaesthesia & Intensive Care Medicine, 2008Abstract The opioid system comprises four receptor subtypes: μ (MOP), κ (KOP), δ (DOP) (i.e. the so-called ‘classical' opioid receptors) and the more recently identified nociceptin/orphanin FQ peptide (N/OFQ) receptor (NOP). Selective endogenous peptides, typically cleaved from larger precursor proteins, have been identified for all subtypes.
McDonald, J, Lambert, DG
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Opioid and non-opioid analgesics
Best Practice & Research Clinical Anaesthesiology, 2003Opioids are the most potent analgesics. Toxicity results either from effects mediated by variation in affinity and intrinsic efficacy at specific opioid receptors or, rarely, from a direct toxic effect of the drugs. For some adverse effects, opioids exhibit a 'dual pharmacology' whereby these effects are usually observed only in pain-free individuals ...
Gail Gillespie +2 more
openaire +3 more sources