Results 21 to 30 of about 2,827 (204)

Suppression of intrahepatic cholangiocarcinoma cell growth by SKI via upregulation of the CDK inhibitor p21

FEBS Open Bio, Volume 12, Issue 12, Page 2122-2135, December 2022., 2022
We analyzed clinical intrahepatic cholangiocarcinoma (CC) samples, focusing on the microRNA‐3648 and its target mRNA, the tumor suppressor Sloan Kettering Institute (SKI). We found that SKI was involved in the transcription of the cyclin‐dependent kinase inhibitor p21. SKI–p21 signaling may act as a brake, preventing cell cycle progression in G1 phase,
Etsushi Kawamura, Tsutomu Matsubara, Atsuko Daikoku, Sanae Deguchi, Masahiko Kinoshita, Hideto Yuasa, Hayato Urushima, Naoshi Odagiri, Hiroyuki Motoyama, Kohei Kotani, Ritsuzo Kozuka, Atsushi Hagihara, Hideki Fujii, Sawako Uchida‐Kobayashi, Shogo Tanaka, Shigekazu Takemura, Keiko Iwaisako, Masaru Enomoto, Y. H. Taguchi, Akihiro Tamori, Shoji Kubo, Kazuo Ikeda, Norifumi Kawada   +22 more
wiley   +1 more source

Perspectives in the vaccine development against Opisthorchis viverrini liver fluke

MedComm – Biomaterials and Applications, Volume 1, Issue 2, September 2022., 2022
The graphical abstract depicts infection with Opisthorchis viverrini, the development of cholangiocarcinoma upon long‐term exposure to extracellular vesicles' secretome content, and the benefits of providing protection by vaccination. Abstract Liver flukes, Opisthorchis viverrini, infect around 10 million individuals in Southeast Asia, alone, and cause
Ahmed O. Shalash, Mariusz Skwarczynski, Istvan Toth   +2 more
wiley   +1 more source

Evaluation of immunodiagnostic tests for human gnathostomiasis using different antigen preparations of Gnathostoma spinigerum larvae against IgE, IgM, IgG, IgG1‐4 and IgG1 patterns of post‐treated patients

Tropical Medicine &International Health, Volume 26, Issue 12, Page 1634-1644, December 2021., 2021
Abstract Objectives The aims of the study were two‐fold: (1) antigen (Ag) preparation and evaluation of three antigens of Gnathostoma spinigerum infective larvae (GsL3), crude somatic antigen (CSAg), excretory‐secretory antigen (ESAg) and partially purified antigens (namely P1Ag, P2Ag and P3Ag) to differentiate IgE, IgG, IgG1–4 and IgM for human ...
Issariya Ieamsuwan, Dorn Watthanakulpanich, Urai Chaisri, Poom Adisakwattana, Paron Dekumyoy   +4 more
wiley   +1 more source

Hypertension as a manifestation of COVID‐19 pneumonia

Clinical Case Reports, Volume 9, Issue 9, September 2021., 2021
Several factors such as hypertension, bile duct disease, and age can affect the duration of COVID, which can lead to long COVID. Any course of coronavirus infection could have a diverse nature of clinical forms and should have a personalized approach. Abstract Several factors such as hypertension, bile duct disease, and age can affect the duration of ...
Makhabbat Bekbossynova, Tauekelova Ainur
wiley   +1 more source

Efficiency of the Stool‐PCR Test Targeting NADH Dehydrogenase (Nad) Subunits for Detection of Opisthorchis viverrini Eggs

Journal of Tropical Medicine, Volume 2021, Issue 1, 2021., 2021
Opisthorchis viverrini infection is the major parasitic infection problem in Southeast Asian countries, and long‐term infection will lead to cholangiocarcinoma (CCA), the bile duct cancer. The early diagnosis of O. viverrini infection may interrupt the progression of the opisthorchiasis and other related illnesses, especially CCA.
Wansika Phadungsil, Supaporn Pumpa, Kridsada Sirisabhabhorn, Amornrat Geadkaew-Krenc, Rudi Grams, Mathirut Mungthin, Toon Ruang-Areerate, Poom Adisakwattana, Nipawan Labbunruang, Pongsakorn Martviset, Pedro P. Chieffi   +10 more
wiley   +1 more source

Opistorchis felineus invasion influence on immunity in bronchial asthma

Бюллетень сибирской медицины, 2010
To investigate the molecular mechanisms of human immune response modification by Opisthorchis felineus antigens in bronchial asthma. The experimental study was performed with cell cultures from patients with bronchial asthma, patients with ...
L. M. Ogorodova, M. B. Freidin, A. E. Sazonov, O. S. Fyodorova, I. A. Deyev, Ye. E. Kremer   +5 more
doaj   +1 more source

Mechanisms of trematodiases pathogenicity: the presence of the secretory proteins from the liver fluke Opisthorchis felineus in the gallbladder tissues of the patients with chronic opisthorchiasis

Вавиловский журнал генетики и селекции, 2017
Opisthorchiasis caused by the liver fluke Opisthorchis felineus infection remains a serious public health problem in the former USSR and Eastern European countries. O.
M. Y. Pakharukova, A. V. Kovner, A. N. Trigolubov, E. N. Fedin, E. S. Mikhailova, S. G. Shtofin, A. I. Autenshlyus, V. A. Mordvinov   +7 more
doaj   +1 more source

Possibilities of application of enterosorbent in combined therapy of opistorchosis patients with skin syndrome

Медицинский совет, 2020
Introduction. Diseases of the liver and biliary tract are a significant problem in the clinic of internal diseases. Opistorchiasis is one of the most frequent causes of this pathology and is one of the most widespread parasitoses in the Russian ...
V. V. Tsukanov, A. V. Vasyutin, J. L. Tonkikh, E. G. Gorchilova, O. S. Rzhavicheva, А. G. Borisov   +5 more
doaj   +1 more source

Preventive behavior of Opisthorchiasis among people in Ubon Ratchathani province, Thailand

Journal of Ideas in Health, 2021
Background: Although we are in the era of the 21st-century, some people's lifestyles are still unchanged. People are still eating crude or undercooked fish, which puts them at risk for opisthorchiasis infection.
Kaewjai Maleelai, Sasimaphon Chaikaew, Aungsumalin Nakham, Jinda Khumkaew   +3 more
doaj   +1 more source

Features of Opisthorchiasis in the Natural Focus

Aktualʹnaâ Infektologiâ, 2014
Introduction. One of the most important epidemiological problems in Sumy region — opisthorchiasis. Social and medical significance of the invasion is great due to high incidence of the disease, the development of severe complications. Purpose. To analyze
N.D. Chemich, N.I. Іlyina, V.V. Zakhlyebayeva, S.Ye. Sholokhova   +3 more
doaj   +1 more source