Results 121 to 130 of about 291,003 (354)

Rubrolides A, D, P, T, U: Total Syntheses and Antibacterial Evaluation of Highly Brominated Marine Natural Products

open access: yesChemistryEurope, EarlyView.
Following the Danube Flow. The first total syntheses of highly brominated rubrolides T, U, and U‐analog, together with the efficient and divergent syntheses of rubrolides A, D, and P. The dibrominated key intermediate, obtained via a Suzuki‐Miyaura cross‐coupling reaction, is the centerpiece of the synthesis.
Jasmin Janneschütz   +7 more
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

open access: yes, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

What Immunological Defects Predispose to Non-tuberculosis Mycobacterial Infections? [PDF]

open access: yes, 2017
Nontuberculous mycobacteria (NTM) are categorized as one of the large and diverse groups of environmental organisms which are abundant in water and soil.  NTM cause a variety of diseases in humans that mainly affect the lung.
Adcock, IM   +7 more
core  

Serious Infection in Crohn's Disease Patients Treated With Ustekinumab: US Food and Drug Administration Active Postmarket Risk Identification and Analysis in the Sentinel Initiative

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The U.S. Food and Drug Administration (FDA) used an Active Postmarket Risk Identification and Analysis (ARIA) system to address a safety issue (serious infection) identified during clinical review of an application to market ustekinumab as a treatment for Crohn's disease (CD). FDA used an active‐comparator new‐user cohort design, data from six Sentinel
Joel L. Weissfeld   +9 more
wiley   +1 more source

The macroecology of immunity: predominant influence of climate on invertebrate immune response

open access: yesEcography, EarlyView.
The immune system is the primary defense against parasites. With the ever‐increasing rate of disease, epidemiologic models considering geographic variation in immune responses could prove useful. Despite increasing interest in the macroecology of parasitism and infectious diseases, we know little about the macroecology of immune responses (i.e ...
Adam Z. Hasik   +9 more
wiley   +1 more source

The HIV/AIDS Epidemic in the United States [PDF]

open access: yes, 2005
Provides key trends related to HIV/AIDS in the U.S., including recent advances in treatment, new HIV testing technologies, the impact of the epidemic by region and population, and the Government's ...

core  

Biodegradable Coatings with Essential Oils for Combating Papaya Anthracnose: State of the Art and Perspectives

open access: yesFood Bioengineering, EarlyView.
ABSTRACT Papaya (Carica papaya L.) production and marketability are strongly constrained by postharvest diseases, with anthracnose caused by Colletotrichum spp. representing the most significant threat. Traditional control relies on synthetic fungicides, which, although effective, face challenges such as the development of pathogen resistance ...
Raul Coimbra Miranda   +5 more
wiley   +1 more source

Analysis of Research on the Effects of Improved Water, Sanitation, and Hygiene on the Health of People Living with HIV and AIDS and Programmatic Implications [PDF]

open access: yes, 2007
This paper reviews the existing scientific and programmatic evidence, raises WASH issues in the HIV and AIDS context that need further study to build the evidence base, assesses current WASH guidance through a review of national HIV/AIDS guidelines from ...

core  

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