Results 51 to 60 of about 155,324 (296)

The opportunistic replacement and inspection problem for components with a stochastic life time [PDF]

open access: yes, 2011
The problem of finding efficient maintenance and inspection schemes in the case of components with a stochastic life time is studied and a mixed integer programming solution is proposed.
Bohlin, Markus   +2 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Development and exploratory cluster-randomised opportunistic trial of a theory-based intervention to enhance physical activity among adolescents [PDF]

open access: yes, 2008
Peer ...
Abraham C   +25 more
core   +1 more source

Long-term effects of intermittent IL-2 in HIV infection: extended follow-up of the INSIGHT STALWART Study [PDF]

open access: yes, 2012
BACKGROUND The Study of Aldesleukin with and without Antiretroviral Therapy (STALWART) was designed to evaluate whether intermittent IL-2 alone or with peri-cycle ART increased CD4+ cell counts (and so delayed initiation of ART) in HIV infected ...
Babiker, Abdel   +8 more
core   +6 more sources

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner   +14 more
wiley   +1 more source

Framework for Managing Maintenance of Wind Farms Based on a Clustering Approach and Dynamic Opportunistic Maintenance

open access: yesEnergies, 2019
The growth in the wind energy sector is demanding projects in which profitability must be ensured. To fulfil such aim, the levelized cost of energy should be reduced, and this can be done by enhancing the Operational Expenditure through excellence in ...
Juan Izquierdo   +3 more
doaj   +1 more source

Optimal maintenance of multi-component systems: a review [PDF]

open access: yes, 2006
In this article we give an overview of the literature on multi-component maintenance optimization. We focus on work appearing since the 1991 survey "A survey of maintenance models for multi-unit systems" by Cho and Parlar.
Dekker, R. (Rommert)   +1 more
core  

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

open access: yesAdvanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen   +7 more
wiley   +1 more source

Condition-based maintenance at both scheduled and unscheduled opportunities [PDF]

open access: yes, 2016
Motivated by original equipment manufacturer (OEM) service and maintenance practices we consider a single component subject to replacements at failure instances and two types of preventive maintenance opportunities: scheduled, which occur due to periodic
Kalosi, Szilard   +2 more
core   +6 more sources

A Reliability-based Opportunistic Predictive Maintenance Model for k-out-of-n Deteriorating Systems

open access: yesChemical Engineering Transactions, 2013
Motivated by the effectiveness of condition-based maintenance (CBM) for single-unit systems, we develop in this paper an opportunistic predictive maintenance model for a k-out-of-n deteriorating system.
K.T. Huynh, A. Barros, C. Berenguer
doaj   +1 more source

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