Results 111 to 120 of about 6,223,039 (287)
Converting Serious Safety Events into Educational Opportunities [PDF]
Over the past year, the Associate Director of the Simulation Center worked with the EM Quality and Safety Director to identify serious safety events (SSE) and critical incidents.
Vitto, Michael Joseph
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
New Opportunities for Solar Through Grid Modernization [PDF]
Lawmakers and utility regulators in California and New York have been extensively engaged in efforts to modernize the electric distribution grid. This paper draws on the experience of Solar Energy Industries Association (SEIA) staff in each jurisdiction ...
Brandon Smithwood, Dave Gahl, Rick Umoff
core
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Large U.S. Crops Provide Opportunities for Producers [PDF]
published or submitted for publicationnot peer ...
Good, Darrel
core
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Sustainable energy: choices, problems and opportunities [PDF]
About the Book: The world's dependence on fossil fuels is widely acknowledged to be a major cause of rising levels of carbon dioxide in the atmosphere.
Elliott, David
core
Cyber Threat Intelligence : Challenges and Opportunities
The ever increasing number of cyber attacks requires the cyber security and forensic specialists to detect, analyze and defend against the cyber threats in almost realtime.
Conti, Mauro +2 more
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source

