Results 61 to 70 of about 1,903,721 (277)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
How to Create Entrepreneurial and Innovative Culture and Sustain it in a Large Organization? [PDF]
, 2014 Research on entrepreneurial culture in large and established organizations is a field that has been growing more and more recently. With foundational research dating as far back as 1970, there was a significant acceleration in corporate entrepreneurship ...
Ameisen, Emmanuel
core +1 more source
Pattern recognition issues on anisotropic smoothed particle hydrodynamics
, 2013 This is a preliminary theoretical discussion on the computational requirements of the state of the art smoothed particle hydrodynamics (SPH) from the optics of pattern recognition and artificial intelligence.
Marinho, Eraldo Pereira
core +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
How to build a nestbox in a wall cavity [PDF]
, 2015 Building conservation is fraught with ethical dilemmas. At one extreme there is pressure to freeze buildings at a particular point in time and another to modernise them beyond all recognition.
Hippisley-Cox, Charles
core
Journal of Business Economics and Management, 2015 Organisational innovation depends on individuals and managers fostering and maintaining the innovative capacities of the firm, where opportunity recognition is important for promoting corporate entrepreneurship.
Boris Urban, Eric Wood
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Projective Methods of Image Recognition [PDF]
, 2008 We propose a method for image recognition on the base of projections. Radon transform gives an opportunity to map image into space of its projections.
Gorohovatsky, Alexey +3 more
core
Cogent Business & ManagementThe circular economy (CE) promotes maximizing product utility and minimizing total material throughput to benefit the environment and economy. Circular innovation is gaining prominence as a path to sustainability alongside the circular economy; however ...
Abdelsalam Adam Hamid +4 more
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source