Results 81 to 90 of about 6,156,970 (335)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Towards a Practical Pedestrian Distraction Detection Framework using Wearables

, 2017
Pedestrian safety continues to be a significant concern in urban communities and pedestrian distraction is emerging as one of the main causes of grave and fatal accidents involving pedestrians.
Crager, Kirsten, He, Jibo, Jadliwala, Murtuza, Maiti, Anindya, Rathore, Heena, Vinayaga-Sureshkanth, Nisha   +5 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

The importance of opportunity recognition behaviour and motivators of employees when engaged in corporate entrepreneurship

Journal of Business Economics and Management, 2015
Organisational innovation depends on individuals and managers fostering and maintaining the innovative capacities of the firm, where opportunity recognition is important for promoting corporate entrepreneurship.
Boris Urban, Eric Wood
doaj   +1 more source

Projective Methods of Image Recognition [PDF]

, 2008
We propose a method for image recognition on the base of projections. Radon transform gives an opportunity to map image into space of its projections.
Gorohovatsky, Alexey, Gorohovatsky, Vladimir, Peredriy, Elena, Putyatin, Yevgeniy   +3 more
core  

High-resolution computed tomography reconstructions of invertebrate burrow systems [PDF]

, 2015
The architecture of biogenic structures can be highly influential in determining species contributions to major soil and sediment processes, but detailed 3-D characterisations are rare and descriptors of form and complexity are lacking.
A La Croix, A Seilacher, DP Bebber, E Bullmore, GH Brimhall, GW Quinn, H Downie, J Dinley, J Schindelin, JD Germano, K Mazik, KM Dorgan, KT Perez, LA Buatois, LA Nickell, M Joschko, M Solan, N Ramnani, O Daniel, R Boistel, R Hale, R Rosenberg, R Rosenberg, R Weiddleder, R. Hale, RB Griffis, RE Martin, S Mairhofer   +27 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Circular economy drivers and sustainable innovation among Omani entrepreneurs: the role of opportunity recognition

Cogent Business & Management
The circular economy (CE) promotes maximizing product utility and minimizing total material throughput to benefit the environment and economy. Circular innovation is gaining prominence as a path to sustainability alongside the circular economy; however ...
Abdelsalam Adam Hamid, Walaa Mohammed Al Habsi, Ramzi Sallem, Nusaiba Abdullah Al-Ghassani, Shamsa Khalfan Al-Himali   +4 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Opportunity Recognition in High Tech and Regulatory Environment: A study of product based Indian Telecom start-ups [PDF]

Opportunity recognition forms the first step of entrepreneurship. Off late entrepreneurship research has looked at opportunity recognition from varied lenses with entrepreneurial learning forming the core of most scholarly work.
Aeron, Prageet, Jain, Rekha
core