Results 31 to 40 of about 697,439 (294)

What is cultural planning? [PDF]

open access: yes, 2008
What is cultural planning about? As always, metaphors secretly direct and limit what we are able to think and formulate. One can, roughly, distinguish between metaphors taken from the mechanical and taken from the organically.
Verschaffel, Bart
core  

Could Turkey’s new parties change the political balance? EPC Policy Brief 13 March 2020 [PDF]

open access: yes, 2020
New political trends are unfolding in Turkey. Recently established political parties have raised hopes for change in the country, impacting the political balance between the government and the opposition.
Paul, Amanda, Seyrek, Demir Murat
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

All I'm asking, is for a little respect: assessing the performance of Britain's most successful radical left party [PDF]

open access: yes, 2012
This article offers an overview of the genesis, development and decline of the Respect Party, a rare example of a radical left party which has achieved some degree of success in the UK.
Peace, Timothy
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

The prospects for a vigorous parliamentary opposition in a democratic South Africa [PDF]

open access: yes, 2007
Student Number: 0516477F DEPARTMENT OF POLITICAL STUDIES THE DEGREE OF MASTER OF ARTSThis research report is a probe into prospects of meaningful political opposition in the parliamentary system South Africa.
Nnadika, Chimezie Amara
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Weltanschauung und Politik in den heutigen USA. Barack Obama und der „neue Kulturkampf“ um die Führung der anglo-amerikanischen Weltmacht [PDF]

open access: yesIntegral Review, 2010
The relationship between Worldviews and Politics in the USA today. Barack Obama and the “new cultural battle” for political supremacy in the US English Summary: This article provides an analysis of the current relationship between Politics, Culture ...
Roland Benedikter
doaj   +2 more sources

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