Results 41 to 50 of about 6,896,729 (296)

Understanding the Barriers to Organ Donation Under Opt-out Legislation [PDF]

, 2021
Background: Although transplantation rates around the world have increased by 7% since 2015, existing rates of transplantation fulfil less than 10% of global need.
Miller, Jordan
core   +1 more source

Practical application of opt-out recruitment methods in two health services research studies

BMC Medical Research Methodology, 2017
Background Participant recruitment is an ongoing challenge in health research. Recruitment may be especially difficult for studies of access to health care because, even among those who are in care, people using services least often also may be hardest ...
Christopher J. Miller, James F. Burgess, Ellen P. Fischer, Deborah J. Hodges, Lindsay K. Belanger, Jessica M. Lipschitz, Siena R. Easley, Christopher J. Koenig, Regina L. Stanley, Jeffrey M. Pyne   +9 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Opt-out organ donation without presumptions

, 2011
This paper defends an 'opt-out' scheme for organ procurement, by distinguishing this system from 'presumed consent' (which the author regards as an erroneous justification of it).
Ben Saunders, Saunders, B., Saunders, Ben   +2 more
core   +1 more source

The Effect of Forced Choice with Constant Choice Experiment Complexity

Journal of Agricultural and Resource Economics, 2019
In a choice experiment, when respondents are not given the opportunity to choose none of the options offered in a choice set, the choices can be considered forced.
Jerrod M. Penn, Wuyang Hu, Linda J. Cox
doaj   +1 more source

A Randomised Controlled Trial of Consent Procedures for the Use of Residual Tissues for Medical Research: Preferences of and Implications for Patients, Research and Clinical Practice. [PDF]

PLoS ONE, 2016
BACKGROUND:Despite much debate, there is little evidence on consequences of consent procedures for residual tissue use. Here, we investigated these consequences for the availability of residual tissue for medical research, clinical practice, and patient ...
S Rebers, E Vermeulen, A P Brandenburg, T J Stoof, B Zupan-Kajcovski, W J W Bos, M J Jonker, C J Bax, W J van Driel, V J Verwaal, M W van den Brekel, J C Grutters, R A Tupker, L Plusjé, R de Bree, J H Schagen van Leeuwen, E G J Vermeulen, R A de Leeuw, R M Brohet, N K Aaronson, F E Van Leeuwen, M K Schmidt   +21 more
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Association between self-reported motivation to quit smoking with effectiveness of smoking cessation intervention among patients hospitalized for acute coronary syndromes in Switzerland

Preventive Medicine Reports, 2021
Guidelines recommend brief smoking cessation interventions for hospitalized smokers reporting low motivation-to-quit. However, an intensive smoking cessation intervention may improve smoking cessation for these smokers.
Inge Worni-Schudel, Vasilis Tzalis, Julian Jakob, Kali Tal, Lauriane Gilgien-Dénéréaz, Baris Gencer, Christian M. Matter, Thomas Felix Lüscher, Stephan Windecker, François Mach, Jean-Paul Humair, Nicolas Rodondi, David Nanchen, Reto Auer   +13 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Identifying compliant participants through data matching improved estimation of intervention efficacy: randomized trials with opt-in/opt-out

, 2019
OBECTIVE: We propose a data-matching approach to estimate intervention efficacy for randomised controlled trials (RCTs) when there is non-compliance to the allocated treatment with induced selection bias. STUDY DESIGN: and Settings: We considered a large
Scuffham, Paul, Ng, Shu Kay, Byrnes, Joshua   +2 more
core   +1 more source