Results 101 to 110 of about 67,593 (295)
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Dominant Optic Atrophy and Sensorineural Hearing-loss
The authors report three patients belonging to three generations of the same family presenting with a dominant optic atrophy; two of these patients (grandfather, mother) also suffered from a mild hearing loss.
Waterschoot, MP. +3 more
core +1 more source
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Aetiological Profile of Optic Atrophy: A hospital based prospective study
Objectives: This study was to evaluateclinical presentations and aetiological profiles of patients with optic atrophy.Methods:The patients had undergone complete ophthalmological examination, i.e.
Agrawal, Shilpi +5 more
core
Objective Obesity, defined by body mass index (BMI) ≥30 kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA ...
Kristine Godziuk +7 more
wiley +1 more source
Segmental Atrophy - Hemianopic (Band) Atrophy from Eight Optic Tract Injury
Segmental Atrophy - Band atrophy from right optic tract injury. Left eye. Has temporal hemianopia with band atrophy. Note loss of nasal nerve fiber layer. Four and a half months after injury from intracranial pressure catheter.
William F. Hoyt, MD
core +1 more source
Optic Coherence Tomography in Patients with Dominant Optic Atrophy
In dominant optic atrophy (DOA), the few available histopathologic reports appear to demonstrate selective loss of retinal ganglion cells with ascending optic atrophy, the loss being most pronounced in the macular area and retinal nerve fiber loss most ...
Dan Milea; Birgit Sander; Marianne Wegener; Hanne Jensen; Birgit Kjer; Henrik Lund-Andersen; Michael Larsen
core
This study presents a reversible temperature sensor with high switching ratio, ∼103. The device is fabricated using PET‐ITO and carbon nanotube dispersions in alkane. Considering its application in cold chain logistics, a proof‐of‐concept with LED is showcased. Thus, a temperature drop below the threshold temperature (crystallization temperature of the
Sunil Kumar Behera +8 more
wiley +1 more source

