Results 151 to 160 of about 67,593 (295)

Myxœdema with Optic Atrophy [PDF]

Proceedings of the Royal Society of Medicine, 1908
openaire   +2 more sources

Low‐Profile, High‐Gain GRIN RF Lenses via Multi‐Material Vat Photopolymerization

Advanced Functional Materials, EarlyView.
We investigate the opportunity of leveraging multi‐material vat photopolymerization printing to manufacture intricate lenses exhibiting permittivity gradients that can increase signal gain in transmitted radiofrequency signals in the X‐ and Ku‐bands. Lenses produced with more distinct low‐loss materials (up to 5) can deliver an 18 dB signal gain with a
Lawrence Romangsuriat, Alexander Peraire‐Bueno, A. John Hart, Randall M. Erb   +3 more
wiley   +1 more source

Reversing Vision Loss and Preventing Optic Atrophy in Leber\u27s Hereditary Optic Neuropathy

, 2013
Leber\u27s hereditary optic neuropathy (LHON) causes profound loss of central vision and optic atrophy. A few reports exist of reversal of vision loss with idebenone or EPI-743 but almost invariably associated with optic atrophy.
Suresh Subramaniam; William Fletcher
core  

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Michele D'Orazio, Biagio Palmisano, Silvia Franco, Arianna Mencattini, Roberta Angelini, Eugenio Martinelli, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +17 more
wiley   +1 more source

Elevated iron levels in tears of patients diagnosed with WDR45 X-linked optic atrophy. [PDF]

Orphanet J Rare Dis
Michelson M, Zahavi A, Zobok T, Yosovich K, Blumkin L, Maharshak I, Lev D, Girshevitz O, Goldenberg-Cohen N.   +8 more
europepmc   +1 more source

IF202b Temporal Cupping with Dominant Hereditary Optic Atrophy

Left eye. Teenage boy. Dominant hereditary optic atrophy (Kjer). Shows temporal pallor only. Shallow temporal cup. Pair with IF2_2a. 1975. Anatomy: Optic disc. Pathology: Dominant hereditary optic atrophy.
William F. Hoyt, MD
core  

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Rhesus macaques with an <i>OPA1</i> mutation demonstrate features of autosomal dominant optic atrophy. [PDF]

Proc Natl Acad Sci U S A
Jaggers TN, Ripolles-Garcia A, Moshiri A, Story BD, Wang J, Chen R, Moore LG, Teixeira LBC, Shim J, Raposo AC, Casanova MI, Le SM, Park S, Young LJ, Kim S, Roszak KP, Ureno V, Karpinen PM, Echeverria N, Ardon M, Leonard BC, Knipe M, Bliss-Moreau E, Fortune B, Stout JT, Rogers J, Marsh-Armstrong N, Thomasy SM.   +27 more
europepmc   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source