Results 151 to 160 of about 354,465 (294)

IF202b Temporal Cupping with Dominant Hereditary Optic Atrophy

Left eye. Teenage boy. Dominant hereditary optic atrophy (Kjer). Shows temporal pallor only. Shallow temporal cup. Pair with IF2_2a. 1975. Anatomy: Optic disc. Pathology: Dominant hereditary optic atrophy.
William F. Hoyt, MD
core  

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Discovery of PHB1 as a Novel Candidate Gene in Dominant Optic Atrophy. [PDF]

Clin Genet
Volk M, Maver A, Vidmar MJ, Trošt N, Višnjar T, Fakin A, Kovač L, Habjan MŠ, Malinar L, Pajić SP, Jerman UD, Romih R, Hawlina M, Peterlin B.   +13 more
europepmc   +1 more source

Walsh & Hoyt: Differential Diagnosis of Optic Atrophy

, 2005
When optic atrophy is complete, it is often impossible to determine its etiology solely from its appearance. Trobe et al. viewed 163 color fundus stereophotographs of nine disease entities: glaucoma, central retinal artery occlusion, ischemic optic ...
Alfredo A. Sadun, MD, PhD; Madhu R. Agarwal, MD
core  

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

From sinusitis to blindness: an unusual case of Pott's puffy tumor with bilateral optic atrophy. [PDF]

Oxf Med Case Reports
Jidal M, Ibat S, Kramchi Y, Jeddab A, Andaloussi MR, Mounir K, Balkhi H.   +6 more
europepmc   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Recessive variants in mitochondrial complex I nuclear subunits are an underrated cause of optic atrophy. [PDF]

Brain
Fiorini C, Jurkute N, Torraco A, La Morgia C, Ghezzi D, Tioli G, Rigobello L, Ormanbekova D, Berghella A, Pasti AP, Palombo F, Barboni P, Cascavilla ML, Sadun F, De Negri A, Bertini E, Musumeci O, Ardissone A, Rizza T, Iarossi G, Silvestri G, Rossi S, Altobelli A, Moore AT, Cullup T, Webster AR, Davagnanam I, Michaelides M, Malka S, Ptackova H, Stufkova H, Tesarova M, Liskova P, Zeng L, Klopstock T, Kopajtich R, Neuhofer C, Prokisch H, Lamperti C, Sadun AA, Yu-Wai-Man P, Carelli V, Musiani F, Iommarini L, Carrozzo R, Arno G, Caporali L.   +46 more
europepmc   +1 more source

Magnetically Driven Biofabrication for Tissue Engineering: From Nanoparticle Design to Mag‐ATMP Translation

Advanced Healthcare Materials, EarlyView.
Magnetically responsive nanoparticles enable remote control over biomaterials, cells, and engineered tissues. This review summarizes material design, biological safety, fabrication and actuation strategies, computational validation, and translational pathways that support the development of magnetic tissue‐engineering platforms and future magnetically ...
Konstantinos Ioannidis, Dimitrios Lefas, Maya Guilliams, Jackie Van Grootenbril, Isaak Decoene, Dimitrios Sakellariou, Bart Smeets, Stefanos Mourdikoudis, Ioannis Papantoniou   +8 more
wiley   +1 more source

OCT-defined optic atrophy thresholds are associated with blunted optic nerve swelling in recurrent optic neuritis. [PDF]

Mult Scler Relat Disord
Syc-Mazurek SB, Liskey D, Tajfirouz DA, Chodnicki KD, Majidi S, Duvigneaud Z, Demortiere S, Stolowy N, Kunchok A, Frohman LP, Stiebel-Kalish H, Zlatkin R, Padungkiatsagul T, Ayzenberg I, Audoin B, Henderson AD, Marignier R, Tilikete CF, Sotirchos ES, Pittock SJ, Flanagan EP, Chen JJ.   +21 more
europepmc   +1 more source