Results 141 to 150 of about 8,823,138 (334)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Optic disc Pit with Retinoschisis in Non-Arteritic Anterior Ischemic Optic Neuropathy

open access: yes, 2023
This case describes a patient with non-arteritic anterior ischemic optic neuropathy and concurrent macular retinoschisis who was later found to have an optic disc pit after resolution of disc edema.
Abraham Hang, MD; Megan M Hughes-Salabar, COA; Yin Allison Liu, MD, PhD
core  

Nutritional optic and peripheral neuropathy: a case report. [PDF]

open access: yes, 2009
INTRODUCTION: The link between nutritional status and either optic or peripheral neuropathies is well established with tobacco, ethanol, deficiencies in thiamine, vitamin A, B12, B3 and B6 and protein-energy malnutrition all being causative.
Nightingale, LM   +3 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Combined optic-flow and stereo-based navigation of urban canyons for a UAV [PDF]

open access: yes, 2005
We present a novel vision-based technique for\ud navigating an Unmanned Aerial Vehicle (UAV) through urban\ud canyons. Our technique relies on both optic flow and stereo\ud vision information. We show that the combination of stereo and optic-flow (stereo-
Roberts, Jonathan M.   +9 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Object representation and distance encoding in three-dimensional environments by a neural circuit in the visual system of the blowfly [PDF]

open access: yes, 2012
Liang P, Heitwerth J, Kern R, Kurtz R, Egelhaaf M. Object representation and distance encoding in three-dimensional environments by a neural circuit in the visual system of the blowfly. Journal of Neurophysiology.
Heitwerth, Jochen   +4 more
core   +1 more source

Amodal Optical Flow

open access: yes2024 IEEE International Conference on Robotics and Automation (ICRA)
Optical flow estimation is very challenging in situations with transparent or occluded objects. In this work, we address these challenges at the task level by introducing Amodal Optical Flow, which integrates optical flow with amodal perception. Instead of only representing the visible regions, we define amodal optical flow as a multi-layered pixel ...
Luz, Maximilian   +6 more
openaire   +5 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Optic flow based perception of two-dimensional trajectories and the effects of a single landmark. [PDF]

open access: yes, 2001
It is well established that human observers can detect their heading direction on a very short time scale on the basis of optic flow (500ms; Hooge et al., 2000). Can they also integrate these perceptions over time to reconstruct a 2D trajectory simulated
Bertin, R.J.V., Israël, I.
core  

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