Results 141 to 150 of about 8,823,138 (334)
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Optic disc Pit with Retinoschisis in Non-Arteritic Anterior Ischemic Optic Neuropathy
This case describes a patient with non-arteritic anterior ischemic optic neuropathy and concurrent macular retinoschisis who was later found to have an optic disc pit after resolution of disc edema.
Abraham Hang, MD; Megan M Hughes-Salabar, COA; Yin Allison Liu, MD, PhD
core
Nutritional optic and peripheral neuropathy: a case report. [PDF]
INTRODUCTION: The link between nutritional status and either optic or peripheral neuropathies is well established with tobacco, ethanol, deficiencies in thiamine, vitamin A, B12, B3 and B6 and protein-energy malnutrition all being causative.
Nightingale, LM +3 more
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Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Combined optic-flow and stereo-based navigation of urban canyons for a UAV [PDF]
We present a novel vision-based technique for\ud navigating an Unmanned Aerial Vehicle (UAV) through urban\ud canyons. Our technique relies on both optic flow and stereo\ud vision information. We show that the combination of stereo and optic-flow (stereo-
Roberts, Jonathan M. +9 more
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Object representation and distance encoding in three-dimensional environments by a neural circuit in the visual system of the blowfly [PDF]
Liang P, Heitwerth J, Kern R, Kurtz R, Egelhaaf M. Object representation and distance encoding in three-dimensional environments by a neural circuit in the visual system of the blowfly. Journal of Neurophysiology.
Heitwerth, Jochen +4 more
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Optical flow estimation is very challenging in situations with transparent or occluded objects. In this work, we address these challenges at the task level by introducing Amodal Optical Flow, which integrates optical flow with amodal perception. Instead of only representing the visible regions, we define amodal optical flow as a multi-layered pixel ...
Luz, Maximilian +6 more
openaire +5 more sources
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Optic flow based perception of two-dimensional trajectories and the effects of a single landmark. [PDF]
It is well established that human observers can detect their heading direction on a very short time scale on the basis of optic flow (500ms; Hooge et al., 2000). Can they also integrate these perceptions over time to reconstruct a 2D trajectory simulated
Bertin, R.J.V., Israël, I.
core

