Results 151 to 160 of about 91,702 (253)
The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease
ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta +11 more
wiley +1 more source
Direction-selective laterodorsal thalamic nucleus encodes optic flow and turning in spatial navigation. [PDF]
Li Z +7 more
europepmc +1 more source
ABSTRACT Background Biallelic FIG4 variants classically cause distinct conditions characterized by peripheral neuropathy (Charcot‐Marie‐Tooth disease type 4J) or skeletal dysplasia (Yunis‐Varón syndrome). However, central nervous system involvement is increasingly recognized. The prevalence and specific characteristics of movement disorders within FIG4‐
Andrea Gangfuß +22 more
wiley +1 more source
Automated generation of ablation lesion masks: a unison of electro and optic flow mapping for persistent AF virtual cohorts. [PDF]
Jaffery OA +8 more
europepmc +1 more source
ABSTRACT Objective Sleep disturbances have been implicated as a risk factor for developing Alzheimer's disease (AD), but evidence linking plasma AD biomarkers to sleep in cognitively unimpaired individuals remains limited. The present study examined associations between evening, morning, and overnight changes in plasma AD biomarkers and measures of ...
Cornelia Sauter +5 more
wiley +1 more source
Distinct temporal dynamics of judging scene-relative object motion and estimating heading from optic flow. [PDF]
Xie M, Li L.
europepmc +1 more source
Parkinson Disease Subtype Stability and Eventual Convergence
ABSTRACT Objective Previous research identified distinct Parkinson disease (PD) clinical subtypes of “Motor Only,” “Psychiatric & Motor,” and “Cognitive & Motor” based on comprehensive, multidomain classification. Whether these subtypes reflect distinct trajectories or progressive disease stages remains unknown.
Laura M. Rosok +10 more
wiley +1 more source
Effects of visual cues on scene-relative object motion judgments and concurrent heading estimation from optic flow. [PDF]
Yang Y, Shan Z, Li L.
europepmc +1 more source
White Matter Hyperintensities Modify CYP2C19 Effect on Stroke Progression in Small Vessel Occlusion
ABSTRACT Background The association between CYP2C19 loss‐of‐function (LOF) alleles and early neurological deterioration (END) in acute small vessel occlusion (SVO) patients receiving dual antiplatelet therapy (DAPT) remains inconsistent. We hypothesized that white matter hyperintensities (WMH) burden act as a key moderator and investigated whether this
Xiaoxin Sun +5 more
wiley +1 more source

