Results 111 to 120 of about 3,501,491 (293)

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Decoding self-motion: insights into visual-vestibular causal inference

Frontiers in Human Neuroscience
Self-motion perception relies on the integration of visual optic flow and vestibular signals, yet these cues are often noisy, unreliable, or mutually inconsistent.
Huizhe Sun, Aihua Chen, Fu Zeng
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Optic flow during real-world locomotion [VIDEO COLLECTION]

, 2016
Preliminary analyses of optic flow stimulus experienced during real-world locomotion. Optic flow estimates were estimated by the Farneback Method function in Matlab's Computer Vision ToolboxRelated manuscripts available here - https://utexas.academia.edu/
Jonathan Matthis (2869172), Mary Hayhoe (554988)   +1 more
core   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Bioinspired event-driven collision avoidance algorithm based on optic flow [PDF]

, 2015
Milde MB, Bertrand O, Benosman R, Egelhaaf M, Chicca E. Bioinspired event-driven collision avoidance algorithm based on optic flow. In: 2015 International Conference on Event-based Control, Communication, and Signal Processing (EBCCSP).
Bertrand, Olivier ; https://orcid.org/, Benosman, Ryad, Egelhaaf, Martin ; https://orcid.org/, Chicca, Elisabetta ; https://orcid.org/, Milde, Moritz B., Benosmanz, Ryad, Egelhaaf, Martin, Chicca, Elisabetta, Olivier J.N. Bertrand, Martin Egelhaaf, Milde, Moritz B, Elisabetta Chicca, Moritz B. Milde, Bertrand, Olivier J N, Ryad Benosmanz   +14 more
core   +1 more source

Changes in cerebral activation in individuals with and without visual vertigo during optic flow: A functional near-infrared spectroscopy study

NeuroImage: Clinical, 2018
Background and purpose: Individuals with visual vertigo (VV) describe symptoms of dizziness, disorientation, and/or impaired balance in environments with conflicting visual and vestibular information or complex visual stimuli.
Carrie W. Hoppes, Patrick J. Sparto, Susan L. Whitney, Joseph M. Furman, Theodore J. Huppert   +4 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source