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Optic Nerve Disease and Axon Pathophysiology

2012
Optic neuropathy is the most common cause of irreversible blindness worldwide. Although the most common optic neuropathy is glaucoma, there are also many other optic neuropathies, for example, those associated with multiple sclerosis, giant cell arteritis, ischemia, and many other diseases.
Leonard A. Levin   +2 more
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The optic nerve

Neurology, 2006
Evaluating pathologic changes in the brain during life has always been an indirect process at best, largely shielded from view by the barrier of the bony skull. Even MRI provides only a computer-analyzed picture of electromagnetic radiation from the nuclei of hydrogen atoms in the brain, excited by radiofrequency pulses in a magnetic field. In a sense,
David A. Drachman, Neil R. Miller
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Standardized A-Scan Echography in Optic Nerve Disease

Ophthalmic Plastic & Reconstructive Surgery, 1987
This study documents the results of standardized A-scan examinations performed in 59 cases of optic nerve lesions (15 perioptic meningiomas, four gliomas, 15 acute neuritides, ten optic atrophies, five ischemic optic neuropathies, five acute central retinal vein occlusions, five traumatic optic neuropathies), as compared with 73 normal optic nerves ...
Joel S. Glaser   +2 more
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Optic Nerve Head and Nerve Fiber Layer in Alzheimer's Disease

Archives of Ophthalmology, 1991
We compared (1) the differences in the retinal nerve fiber layer between 26 patients with Alzheimer's disease and 30 age- and race-matched normal controls with use of blue-light high-resolution photography, (2) the differences in disc pallor between 30 patients with Alzheimer's disease and 32 controls with use of a boundary-tracking program and fundus ...
Neil R. Miller   +6 more
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Color discrimination in optic nerve diseases

Neuro-Ophthalmology, 1985
The characteristics of color discrimination of 71 eyes in 49 patients with optic nerve diseases were examined using the Farnsworth-Munsell 100-Hue test (F-M 100 Hue test). The orientation axes of the hue errors of the F-M 100 Hue test were analyzed objectively using the method recommended by Kitahara (1982).As a result, the mean value of the amplitude ...
Mari Nishimuta, Kenji Kitahara
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Optic nerve edema as a consequence of respiratory disease

Neurology, 1999
The authors describe a patient with bilateral papilledema, visual field abnormalities, poorly reactive pupils, meningeal enhancement on cranial MRI, and diffuse brain parenchymal hypervascularity. The opening pressure at the time of lumbar puncture was normal, and results of other CSF studies were normal.
Henry S. O'Halloran   +5 more
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Racial variation of optic nerve diseases

Neuro-Ophthalmology, 1991
The authors analyzed the racial distribution of optic nerve head drusen and nonar-teritic ischemic optic neuropathy in a clinical setting. Blacks had a significantly much lower incidence of these two disorders than whites. Knowing previously that both disc drusen and nonarteritic ischemic optic neuropathy are associated with small discs, and that ...
Ahmad M. Mansour, Latif M. Hamed
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Congenital Diseases of the Optic Nerve

2016
Congenital diseases of the visual pathway include developmental abnormalities and hereditary diseases. The recognition of developmental abnormalities, i.e., congenital optic disc anomalies is of great significance. On the one hand, they are not rare; on the other hand, they can cause a differential diagnostic challenge: they can be confused with ...
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Visual dysfunction in retinal and optic nerve disease

Neurologic Clinics, 2003
Visual perceptions seen with retinal and optic nerve disease may overlap with those resulting from retrochiasmal disorders. A few disorders typically present with distinctive perceptions, but the majority have less specific symptoms. Features include whether or not the visual phenomena are negative or positive, monocular or binocular, and the location ...
Timothy J. Murtha, Steven F. Stasheff
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Inherited or Congenital Optic Nerve Diseases

2010
In this chapter, we discuss inherited/congenital optic nerve diseases and their related visual fields defects. It is important for the ophthalmologist to establish, on the basis of the visual fields defect whether the optic nerve is involved and, if so, whether this is at the level of the optic disc or further back.
Peter A. Quiros, Alfredo A. Sadun
openaire   +1 more source

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