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Gene therapy in optic nerve disease
Current Opinion in Ophthalmology, 2018Highlight some of the recent advances in gene therapy and gene modification for optic nerve disease to promote axon regeneration, neuroprotection, and increased visual functioning.Visual loss secondary to optic nerve damage occurs in numerous ophthalmologic and neurologic conditions.
Adam, DeBusk, Mark L, Moster
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Optic nerve involvement in Lyme disease
Current Opinion in Ophthalmology, 2012The tick-borne spirochete Borrelia burgdorferi sensu lato can cause several neural manifestations from the peripheral and central neural system. There are several case reports in the literature of optic nerve involvement in association with Lyme neuroborreliosis, but clinical guidelines as to when Lyme disease should be considered in optic neuropathy ...
Frank, Träisk, Lars, Lindquist
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2021
Nowadays different modalities are available for the diagnosis of optic nerve diseases, as visual field test, electrophysiology, OCT on the optic nerve, CT scan and MRI scan. Ultrasound is one of the reliable modality for the diagnosis of optic nerve diseases as it can provide information that is not easily accessible with other investigative modalities.
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Nowadays different modalities are available for the diagnosis of optic nerve diseases, as visual field test, electrophysiology, OCT on the optic nerve, CT scan and MRI scan. Ultrasound is one of the reliable modality for the diagnosis of optic nerve diseases as it can provide information that is not easily accessible with other investigative modalities.
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Orbital disease, optic nerve and chiasm
Current Opinion in Neurology, 1997The diagnosis and management of diseases of the orbit, optic nerve and chiasm continue to evolve. Advances in neuroradiology are remarkable and continue to expand diagnosis and management. This review will highlight the clinical assessment of disease, orbital and neuroimaging, medical and surgical management.
K P, Cockerham, J S, Kennerdell
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Optic Nerve Damage in Alzheimer's Disease
Ophthalmology, 1990Optic nerves from ten patients with Alzheimer's disease were histologically examined and compared with those from age-matched controls. Specific and nonspecific measures of degeneration were noted in eight of ten Alzheimer's disease optic nerves; no degeneration was noted in any of the controls.
A A, Sadun, C J, Bassi
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Adrenoleukodystrophy by Disease of the Eye and Optic Nerve
American Journal of Ophthalmology, 1976Adrenoleukodystrophy is an X-chromosome-linked recessive disease characterized by primary atrophy of the adrenal glands with or without Addison's disease and low plasma cortisol levels, and a degeneration of white matter of the central nervous system with blindness.
S H, Wray +4 more
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The Pattern Electroretinogram in Optic Nerve Disease
Ophthalmology, 1983Pattern evoked electroretinograms (PERG), diffuse flash electroretinograms (ERG) and visual evoked potentials were studied in patients with unilateral optic nerve disease. Patients with Snellen acuities of less than 6/30 did not have recordable PERGs in their affected eye, whereas their diffuse flash ERGs were normal.
W, Seiple +4 more
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Optic Nerve Disease and Axon Pathophysiology
2012Optic neuropathy is the most common cause of irreversible blindness worldwide. Although the most common optic neuropathy is glaucoma, there are also many other optic neuropathies, for example, those associated with multiple sclerosis, giant cell arteritis, ischemia, and many other diseases.
Alireza, Ghaffarieh, Leonard A, Levin
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ARTERIOSCLEROTIC DISEASE OF THE OPTIC NERVE
Archives of Ophthalmology, 1931Arteriosclerosis may cause a disturbance in the function of the optic nerves varying from partial disability to complete optic atrophy. This seems to be a fairly widely accepted clinical view, and yet this factor in disease of the optic nerve receives scant attention.
B. J. ALPERS, I. J. WOLMAN
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