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Optic Neuritis

New England Journal of Medicine, 2001
Patients with signs and symptoms consistent with acute monosymptomatic optic neuritis should undergo evaluation with gadolinium-enhanced MRI of the brain and orbits to determine whether or not they are at high risk for the development of clinically definite multiple sclerosis (CDMS).
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Optic Neuritis

Neurologic Clinics, 1991
Optic neuritis can be mimicked by ophthalmologic, neurosurgical, and other conditions. In many if not all cases, optic neuritis may be a manifestation of multiple sclerosis. An ongoing treatment trial may provide answers about whether or not treatment improves outcome.
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Lyme optic neuritis

Journal of the Neurological Sciences, 2010
Lyme optic neuritis (ON) is a rare disease and only a few cases have been reported. We describe two cases of isolated Lyme ON, one with recurrence 9 months after the appearance of initial symptoms. Diagnosis criteria for multiple sclerosis and neuromyelitis optica were not met.
Frédéric, Blanc   +5 more
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Optic neuritis

Current Opinion in Ophthalmology, 1998
Advances in magnetic resonance (MR) orbital imaging using fat suppression techniques and contrast enhancement have increased our ability to visualize the area of inflammation in patients with optic neuritis. Our understanding of the natural history of optic neuritis continues to expand.
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Optic neuritis

Current Opinion in Neurology, 1995
A major breakthrough in the therapy of demyelinating disease has recently been disclosed by the Optic Neuritis Treatment Trial. Over the past 6 years the trial has accumulated evidence that a high dose of corticosteroids taken to treat patients with an isolated acute attack of optic neuritis reduces the rate at which multiple sclerosis develops over a ...
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Optic neuritis in a child

Pediatric Emergency Care, 1996
A previously healthy four-year-old girl developed bilateral loss of vision over one day. Her course of optic nerve abnormalities, a related neurologic episode, and the response to corticosteroid therapy is presented. The diagnosis of optic neuritis in a child is made infrequently in an emergency department, but it must be considered in any patient ...
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Chiasmal Optic Neuritis

Archives of Ophthalmology, 1958
Inflammatory affections of the optic chiasm are probably more frequent than existing records show. According to Duke-Elder, 1 they are seldom recognized. Chiasmal optic neuritis is merely a variant of the well-known condition retrobulbar neuritis. The age and sex incidence of the former corresponds to that of the ordinary case of retrobulbar neuritis,
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Optic neuritis

Neurology, 1990
We studied 20 patients with acute optic neuritis prospectively for 12 months. Visual fields, color vision, and VEPs to 15' checks were initially abnormal in all patients. Visual acuity was abnormal in 90% and contrast sensitivity in 95% of patients. We devised a graded visual impairment scale (GVIS) to include all visual functions tested.
G G, Celesia   +6 more
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Cytomegalovirus optic neuritis

Current Opinion in Ophthalmology, 1997
Cytomegalovirus (CMV) optic neuritis is a rapidly blinding disease. Untreated eyes have a final visual acuity of no light perception. Treated eyes maintain visual acuity of approximately 20/100. Relapse occurs often in subjects maintained on single-dose ganciclovir and is controlled by double-dose ganciclovir.
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Acute optic neuritis

Current Treatment Options in Neurology, 1999
In acute monosymptomatic optic neuritis, treatment with oral prednisone alone should be avoided. Therapy with intravenous methylprednisolone (1 g/day for 3 days) followed by 11 days of oral prednisone (1 mg/kg with a short taper) should be considered instead.
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