Results 11 to 20 of about 219,653 (257)

Atypical optic neuritis – a case with a new surprise every visit

open access: yesGMS Ophthalmology Cases, 2020
Demyelination is the most common cause of optic neuritis. Typical optic neuritis needs intravenous steroids followed by tapering dose oral steroids. Atypical optic neuritis entails clinical manifestations that deviate from the classic pattern of features.
Kaur, Kirandeep   +2 more
doaj   +2 more sources

Optic neuritis [PDF]

open access: yesThe Lancet Neurology, 2014
Acute optic neuritis is the most common optic neuropathy affecting young adults. Exciting developments have occurred over the past decade in understanding of optic neuritis pathophysiology, and these developments have been translated into treatment trials.
Toosy, AT, Mason, DF, Miller, DH
core   +5 more sources

Current options for the treatment of optic neuritis

open access: yesClinical Ophthalmology, 2012
John H Pula,1 Christopher J MacDonald21Division of Neuro-ophthalmology, University of Illinois College of Medicine at Peoria, Peoria; 2University of Illinois College of Medicine at Urbana-Champaign, Champaign, IL, USAAbstract: Optic neuritis can be ...
Pula JH, MacDonald CJ
doaj   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children. [PDF]

open access: yesAnn Clin Transl Neurol
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Aduru C   +13 more
europepmc   +2 more sources

Development of a novel model of optic neuritis to assess neuroprotective and repair strategies in multiple sclerosis [PDF]

open access: yes, 2012
PhDMultiple sclerosis (MS) is a putative autoimmune disease of the central nervous system (CNS), which often affects the optic nerve pathway. Optic neuritis (ON) is a clinical feature of MS that can cause loss of vision due to conduction block and ...
Lidster, Katie
core   +4 more sources

Upadacitinib Restrains the Pathogenic Fitness of CD4<sup>+</sup> T Cells and Aberrant B Cell Programming in Optic Neuritis. [PDF]

open access: yesAdv Sci (Weinh)
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Jiang G   +12 more
europepmc   +2 more sources

Bilateral Simultaneous Optic Neuritis Following Envenomations by Indian Cobra and Common Krait

open access: yesToxins, 2022
In India, most snakebite envenomation (SBE) incidents are caused by the “Big Four” snakes which include Russell’s viper, common krait, Indian cobra, and saw-scaled viper.
Subramanian Senthilkumaran   +5 more
doaj   +1 more source

Approach to optic neuritis: An update

open access: yesIndian Journal of Ophthalmology, 2021
Over the past few years, there has been remarkable development in the area of optic neuritis. The discovery of new antibodies has improved our understanding of the pathology of the disease.
Swati Phuljhele   +2 more
doaj   +1 more source

Clinical Characteristics and Visual Outcomes of Pediatric Optic Neuritis: A Single Center Experience

open access: yesVan Tıp Dergisi, 2022
INTRODUCTION: The aim of this study was to describe the clinical characteristics, visual outcomes of pediatric patients presenting with first-episode of optic neuritis.
Dilek Cebeci   +10 more
doaj   +1 more source

Characteristics of Lyme optic neuritis: a case report of Lyme associated bilateral optic neuritis and systematic review of the literature

open access: yesBMC Neurology, 2022
Optic Neuritis is rare in Lyme borreliosis. The current knowledge of optic nerve involvement in Lyme borreliosis relies solely on case reports. The aim of this systematic review was to characterize and investigate the associated factors of optic neuritis
Yezhong Lu, Ramin Zand
doaj   +1 more source

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