Results 61 to 70 of about 219,653 (257)

Pediatric optic neuritis [PDF]

Neurology, 2016
Optic neuritis (ON) is a common presenting symptom in pediatric CNS demyelinating disorders and may be associated with dramatic visual loss. Knowledge regarding clinical presentation, associated diseases, therapy, and outcomes in ON in children has grown over the past decade. These studies have shown that younger children (
E Ann, Yeh, Jennifer S, Graves, Leslie A, Benson, Evangeline, Wassmer, Amy, Waldman   +4 more
openaire   +2 more sources

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim, Anat Abramovich, Sara Via‐Dorembus, Gali Heimer, Bruria Ben‐Zeev, Etai Adam, Assaf A. Barg, Jonathan Roth, Basheer Sheick‐Yousif, Rony Beeri Berkowiz, Michal Feldon, Haim Bassan, Moran Hausman‐Kedem   +12 more
wiley   +1 more source

To study visual evoked potential in patients with optic nerve diseases

Journal of Clinical Ophthalmology and Research
Background: To study Visual Evoked Potential in patients with Optic Nerve diseases. Study design and settings: Cross – Sectional study. Material and Methods: 72 patients were included in our study, aged 12 years and above, diagnosed as optic nerve ...
Kavita Poonia, Rajeev Tuli, Gaurav Sharma, Amit Bhardwaj   +3 more
doaj   +1 more source

Bilateral Optic Neuritis After Bee Sting

, 2014
Corneal edema, hyphema, lens dislocation, iris atrophy, cataract and glaucoma cases due to bee sting are frequently reported. Optic neuropathy developing after a bee sting is rarely reported. A 46-year-old man applied to our clinic with visual loss.
Haluk Esgin, Turkyilmaz, Yusuf, Yusuf Türkyılmaz, Esgin, Haluk   +3 more
core   +1 more source

Innovative PLA or PCL‐Based Ocular Implants Obtained From Tape Casting or Electrospinning for Sustained‐Release Dexamethasone

Journal of Applied Polymer Science, EarlyView.
PLA and PCL ocular implants prepared by tape casting and electrospinning provide sustained dexamethasone release with distinct release profiles governed by polymer type and processing method. The relationship between polymer structure, degradation behavior, and drug release demonstrates the potential of these fabrication techniques for controlled ...
Renata Bochanoski, Henrique Borba Modolon, Ronaldo Silveira, Januara Rodrigues, Tiago Bender Wermuth, Sabrina Arcaro, Oscar R. K. Montedo   +6 more
wiley   +1 more source

DIFFERENTIAL DIAGNOSIS OF OPTIC NEURITIS [PDF]

Sanamed, 2013
: Optic neuritis is inflammation of the optic nerve, which in a single or repeated attacks can severely and permanently damage visual function. Errors in diagnostic are daily and usually occur because of incomplete diagnostic procedure performed.
Zoric Lepsa, Stojicevic Snezana, Bukumiric Zoran   +2 more
doaj   +2 more sources

Rodent Models of Optic Neuritis

Frontiers in Neurology, 2020
Optic neuritis (ON) is an inflammatory attack of the optic nerve that leads to visual disability. It is the most common optic neuropathy affecting healthy young adults, most commonly women aged 20–45 years.
Yael Redler, Michael Levy
doaj   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

Optic neuritis and its follow-up with optical coherence tomography (OCT) Case report [PDF]

, 2009
Objetivo: Describir las formas de presentación de la neuritis óptica, haciendo énfasis en el síndrome postviral y la neuritis óptica postviral, entidades que van de la mano, mostrando sus asociaciones de tipo local y sistémico. Adicionalmente, se muestra
Gonzales, Carolina, Cárdenas Angelone, Pedro Luis, Hernández, German, Parra Restrepo, Juan Camilo   +3 more
core