Results 61 to 70 of about 64,115 (273)

Fourier Ptychographic Neural Network Combined with Zernike Aberration Recovery and Wirtinger Flow Optimization

open access: yesSensors
Fourier ptychographic microscopy, as a computational imaging method, can reconstruct high-resolution images but suffers optical aberration, which affects its imaging quality. For this reason, this paper proposes a network model for simulating the forward
Xiaoli Wang   +5 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Realization of Zero-Refractive-Index Lens with Ultralow Spherical Aberration

open access: yes, 2016
Optical complex materials offer unprecedented opportunity to engineer fundamental band dispersion which enables novel optoelectronic functionality and devices. Exploration of photonic Dirac cone at the center of momentum space has inspired an exceptional
Chang, Ming-Li   +7 more
core   +2 more sources

Electromagnetic focusing through a tilted dielectric interface [PDF]

open access: yes, 2002
Focusing through a tilted dielectric interface is studied, and an explicit expression for the electric field in the focal region is found. In the case of small tilt angles, one obtains a focal shift, and only a simple aberration term remains.Comment: 8 ...
Ando   +17 more
core   +2 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

The Gaussian formula and spherical aberration of the static and moving curved mirrors from Fermat's principle

open access: yes, 2011
The Gaussian formula and spherical aberrations of the static and relativistic curved mirrors are analyzed using the optical path length (OPL) and Fermat's principle. The geometrical figures generated by the rotation of conic sections about their symmetry
Baker T Y   +9 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Ray Tracing Methods for Correcting Chromatic Aberrations in Imaging Systems

open access: yesInternational Journal of Optics, 2014
The correction of chromatic aberrations is typically performed using aberration formulas or by using real ray tracing. While the use of aberration formulas might be effective for some simple optical systems, it has limitations for complex and fast ...
Dmitry Reshidko   +2 more
doaj   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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