Results 81 to 90 of about 2,756,584 (366)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Ray Tracing Methods for Correcting Chromatic Aberrations in Imaging Systems

International Journal of Optics, 2014
The correction of chromatic aberrations is typically performed using aberration formulas or by using real ray tracing. While the use of aberration formulas might be effective for some simple optical systems, it has limitations for complex and fast ...
Dmitry Reshidko, Masatsugu Nakanato, José Sasián   +2 more
doaj   +1 more source

Methanol immersion reduces spherical aberration of water dipping lenses at long wavelengths used in multi-photon laser scanning microscopy [PDF]

, 2012
Dipping objectives were tested for multi-photon laser scanning microscopy, since their large working distances are advantageous for thick specimens and the absence of a coverslip facilitates examination of living material.
Bestvater, Bolin, Booth, Booth, Cahalan, Demenikov, Denk, Débarre, Débarre, Ganic, Hell, Helmchen, Jacobsen, Ji, Kao, Mann, Marsh, Neil, Norris, Rueckel, Saavedra, Sheppard, Sheppard, Sheppard, Sheppard, Tang, Theer, Wan, Wilson   +28 more
core   +1 more source

Classification robustness to common optical aberrations

2023 IEEE/CVF International Conference on Computer Vision Workshops (ICCVW), 2023
Computer vision using deep neural networks (DNNs) has brought about seminal changes in people's lives. Applications range from automotive, face recognition in the security industry, to industrial process monitoring. In some cases, DNNs infer even in safety-critical situations.
Müller, P., Braun, A., Keuper, M.
openaire   +3 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Fourier Ptychographic Neural Network Combined with Zernike Aberration Recovery and Wirtinger Flow Optimization

Sensors
Fourier ptychographic microscopy, as a computational imaging method, can reconstruct high-resolution images but suffers optical aberration, which affects its imaging quality. For this reason, this paper proposes a network model for simulating the forward
Xiaoli Wang, Zechuan Lin, Yan Wang, Jie Li, Xinbo Wang, Hao Wang   +5 more
doaj   +1 more source

Miniature optical planar camera based on a wide-angle metasurface doublet corrected for monochromatic aberrations

, 2016
Optical metasurfaces are two-dimensional arrays of nano-scatterers that modify optical wavefronts at subwavelength spatial resolution. They are poised to revolutionize optics by enabling complex low-cost systems where multiple metasurfaces are ...
Arbabi, Amir, Arbabi, Ehsan, Faraon, Andrei, Han, Seunghoon, Horie, Yu, Kamali, Seyedeh Mahsa   +5 more
core   +1 more source

An integrated imaging sensor for aberration-corrected 3D photography

Nature, 2022
Planar digital image sensors facilitate broad applications in a wide range of areas1–5, and the number of pixels has scaled up rapidly in recent years2,6.
Jiamin Wu, Yuduo Guo, Chao Deng, Anke Zhang, Hui Qiao, Zhi Lu, Jiachen Xie, Lu Fang, Qionghai Dai   +8 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source