Results 51 to 60 of about 201,426 (331)
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Passive alignment stability and auto-alignment of multipass amplifiers based on Fourier transforms
, 2019 The stability properties of Fourier-based multipass amplifier to misalignments (tilts) of its optical components has been investigated. For this purpose, a method to quantify the sensitivity to tilts based on the amplifier small signal gain has been ...
Antognini, Aldo +10 more
core +1 more source
Wavelength conversion up to 18 nm at 10 Gb/s by four-wave mixing in a semiconductor optical amplifier [PDF]
, 1997 We characterize the conversion bandwidth of a four-wave mixing semiconductor optical amplifier wavelength converter. Conversion of 10-Gb/s signals with bit-error-rate (BER) performance of
Geraghty, David F. +5 more
core +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Optical Fiber Amplifiers: Optimization and PerformanceEvaluation
Diyala Journal of Engineering Sciences, 2019 This work demonstrates the simulation of two different types of optical fiber amplifiers (OFA) utilizing OptiSystem–10, namely, 3 m length of erbium doped fiber amplifier (EDFA) and 7 km length of Raman fiber amplifier (RFA).
A. k. Abass +4 more
doaj +1 more source
Entropy, 2021 An improved continuous variable quantum key distribution (CVQKD) approach based on a heralded hybrid linear amplifier (HLA) is proposed in this study, which includes an ideal deterministic linear amplifier and a probabilistic noiseless linear amplifier ...
Yin Li +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Transverse magnetic mode nonreciprocal propagation in an amplifying AlGaInAs/InP optical waveguide isolator. [PDF]
, 2006 International audienceThe design, fabrication, and characterization of an amplifying transverse magnetic ͑TM͒-mode optical waveguide isolator operating at a wavelength of 1300 nm are presented.
Bart Moeyersoon +11 more
core +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source