Results 71 to 80 of about 90,037 (273)

Optimization of Very Short Multi-Pump Discrete Raman Amplifiers based on Tellurite Fibers

Journal of Microwaves, Optoelectronics and Electromagnetic Applications
This paper presents a numerical study and the optimization of very short discrete multi-pump Raman amplifiers using Tellurite-based optical fibers. While most studies about discrete Raman amplifiers usually focus on cases where hundreds of meters of ...
Gabriel C. Bastida, Helder R. de O. Rocha, Marcelo E. V. Segatto, Carlos E. S. Castellani   +3 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Ion-Exchanged Glass Waveguide Technology: A Review [PDF]

, 2011
We review the history and current status of ion exchanged glass waveguide technology. The background of ion exchange in glass and key developments in the first years of research are briefly described.
Honkanen, Seppo, Tervonen, Ari, West, Brian R.   +2 more
core   +2 more sources

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Hybrid distributed Raman/EDFA amplifier with hybrid automatic gain control for reconfigurable WDM optical networks

Journal of Microwaves, Optoelectronics and Electromagnetic Applications
Nowadays, optical amplifiers designs are induced by new requirements generated by optical networks. The introduction of WDM reconfigurable networks with increasing rate from 10-40 Gb/s to 100 Gb/s and beyond, demand new optical amplifiers development ...
Juliano R. F. Oliveira, Uiara C. Moura, Júlio C. R. F. Oliveira, Murilo A. Romero   +3 more
doaj   +1 more source

Nonuniversality of quantum noise in optical amplifiers operating at exceptional points

Physical Review Research, 2022
The concept of exceptional points-based optical amplifiers (EPOAs) has been recently proposed as a new paradigm for miniaturizing optical amplifiers while simultaneously enhancing their gain-bandwidth product.
L. Simonson, S. K. Ozdemir, A. Eisfeld, A. Metelmann, R. El-Ganainy   +4 more
doaj   +1 more source

Polarization-dependent optical nonlinearities of multiquantum-well laser amplifiers studied by four-wave mixing [PDF]

, 1997
We present a detailed study of the polarization properties of four-wave mixing in multiquantum-well (MQW) semiconductor optical amplifiers (SOA's). In particular, the polarization selection rules relevant to all processes contributing to the generation ...
Hunziker, Guido, Koren, Uzi, Paiella, Roberto, Vahala, Kerry J.   +3 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source