Results 51 to 60 of about 2,198,954 (282)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Comparison of optical biometry and applanation ultrasound measurements of the axial length of the eye [PDF]

open access: yes, 2014
PurposeTo investigate the relationship between optical biometry and applanation ultrasound measurement of the axial length of the eye.Materials and methodsThis prospective study enrolled 55 (68 eyes) consecutive patients scheduled for cataract surgery at
Nakhli, Fouad R.
core   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec   +6 more
wiley   +1 more source

Evaluation of Axial Length Changes after Combined Phacovitrectomy for Macula-off Rhegmatogenous Retinal Detachment

open access: yesBeyoglu Eye Journal, 2019
INTRODUCTION[|]To evaluate the reliability of optical biometry for correct intraocular lens (IOL) power calculation in eyes with macula-off rhegmatogenous retinal detachment (RRD) via comparing the axial lengths (AL) measured with optical biometry ...
Sadık Altan Özal   +3 more
doaj   +1 more source

Variations in Lens Thickness Affecting the Anterior Chamber Length and Their Potential Measurement Using a Biometer

open access: yesPhotonics, 2023
Biometry is a critical aspect of ophthalmology, since it facilitates the measurement of several ocular parameters and aids in the diagnosis of conditions like glaucoma.
F. Javier Povedano-Montero   +4 more
doaj   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub   +24 more
wiley   +1 more source

Comparison of optical coherence biometry and applanation ultrasound biometry in high-myopic eyes with posterior pole staphyloma

open access: yes, 2007
We compared the refractive outcomes of optical coherence biometry and applanation ultrasound biometry in 17 high-myopic eyes with posterior pole staphylorna.
Ozdamar, Akif   +2 more
core   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

A new non-contact optical device for ocular biometry [PDF]

open access: yesBritish Journal of Ophthalmology, 2002
A new commercially available device (IOLMaster, Zeiss Instruments) provides high resolution non-contact measurements of axial length (using partial coherent interferometry), anterior chamber depth, and corneal radius (using image analysis). The study evaluates the validity and repeatability of these measurements and compares the findings with those ...
J, Santodomingo-Rubido   +3 more
openaire   +2 more sources

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

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