Results 131 to 140 of about 4,168 (258)

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

open access: yesMed Research, EarlyView.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Recent Advances in Stimuli-Responsive Membranes: From Supramolecular Design to Controlled Permeability. [PDF]

open access: yesMembranes (Basel)
Moffa S   +6 more
europepmc   +1 more source

Aberrant Beta‐Band Network Alteration Preceding Freezing of Gait in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Freezing of gait (FOG) is a debilitating motor symptom observed in the advanced stages of Parkinson's disease (PD), characterized by an abrupt inability to initiate or continue forward walking. Whole‐brain functional connectivity analysis has shown promise in elucidating the underlying pathophysiology and identifying potential ...
Yanqiu Tian   +3 more
wiley   +1 more source

Predicting Drop‐Weight Impact Sensitivity From Molecular Graphs Using Physics‐Informed Artificial Intelligence

open access: yesPropellants, Explosives, Pyrotechnics, EarlyView.
This work presents an approach for predicting the drop‐weight impact sensitivity of pure molecular explosives directly from 2D molecular graphs using physics‐informed artificial intelligence (AI) models. A dataset comprising experimentally measured sensitivities for 625 unique high‐explosive molecules is augmented with physics‐informed synthetic ...
Grant Hutchings   +4 more
wiley   +1 more source

Opportunities for 2D‐Material‐Based Multifunctional Devices and Systems in Bioinspired Neural Networks

open access: yesSmall, EarlyView.
Bio‐inspired computing offers a route to highly energy‐efficient artificial intelligence. The unique physical properties of two‐dimensional (2D) materials can further enhance such computing approaches. This perspective highlights recent developments in 2D materials‐based neuromorphic devices and discusses future opportunities for integrating such novel
Jin Feng Leong   +9 more
wiley   +1 more source

High Sensitivity Cardiac Troponin I Detection via MP‐Locked Aptamer and Multimeric DNAzyme‐Coupled Hyperbranched Hybridization Chain Reaction

open access: yesSmall, EarlyView.
We report a magnetic particle anchored locked aptamer platform integrated with hyperbranched HCR and DNAzyme amplification for enzyme‐free, ultrasensitive detection of cardiac troponin I. The assay achieves a 0.25 ng/L detection limit within 25 minutes and enables cross‐species MI detection, with machine learning classification reaching 90% accuracy ...
Sayantan Tripathy   +9 more
wiley   +1 more source

All-optical strategies to minimize photobleaching in reversibly switchable fluorescent proteins. [PDF]

open access: yesNat Commun
Marín-Aguilera G   +8 more
europepmc   +1 more source

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