Results 131 to 140 of about 4,557,199 (257)

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos   +7 more
wiley   +1 more source

Optical Character Recognition

open access: yes, 2012
Our project aimed to understand, utilize and improve the open source Optical Character Recognizer (OCR) software, OCRopus, to better handle some of the more complex recognition issues such as unique language alphabets and special characters such as ...
Ben Haddej, Dhia elhak   +1 more
core   +2 more sources

Simulation‐Based Nonlinear Site Amplification Models for Western United States

open access: yesEarthquake Spectra, Volume 42, Issue 4, November 2026.
This article presents one of the first nonlinear (NL) site amplification models relative to VS30 of 800 m/s for the Western United States (WUS) for both the smoothed effective amplitude spectrum (EAS), described as the orientation‐independent horizontal‐component Fourier amplitude spectrum (FAS) of ground acceleration, and the response spectra (RS ...
Okan Ilhan   +5 more
wiley   +1 more source

Tailored Amino Acid Treatment for Pediatric Patients With Mitochondrial Aminoacyl‐tRNA Synthetase Deficiencies

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Aminoacyl‐tRNA synthetases (ARSs) facilitate the loading of transfer RNAs with their cognate amino acids in the cytosol (ARS1), mitochondria (ARS2), or both (dual ARS). ARS deficiencies are clinically heterogeneous and can cause severe, occasionally fatal disease.
I. J. J. Muffels   +21 more
wiley   +1 more source

Dichloroacetate Improves Animal Survival, Growth, Neuromuscular Activity, Mitochondrial Stress and Physiology, and Elevated Lactate in C. elegans pdha‐1 and dld‐1 RNAi Models of Pyruvate Dehydrogenase Complex Deficiency (PDCD)

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Pyruvate dehydrogenase complex (PDHc) deficiency (PDCD) is a primary mitochondrial disorder characterized by neurodevelopmental disability, altered intermediary metabolism, and early mortality. Dichloroacetate (DCA), a pyruvate analog, activates PDHc and remains under clinical investigation for treatment of PDCD.
Cristina Remes   +10 more
wiley   +1 more source

Evaluating the Effectiveness of Open‐Source LLMs for Automated Analysis of Multilingual Consultation Feedback: A Swiss Case Study

open access: yesPolicy Studies Journal, Volume 54, Issue 4, November 2026.
ABSTRACT Public consultations are a cornerstone of democratic policymaking, yet the sheer volume and heterogeneity of submissions often overwhelm traditional analysis. Emerging large language models (LLMs) offer new opportunities for making sense of such data, but their performance in contexts with high linguistic and technical diversity remains ...
Edgar Mathevet, Lauriane Cailleux
wiley   +1 more source

Increased Expression of Desmin and Vimentin Impairs Mitochondrial Function and Reduces Contractility via G0S2 in Bladder Smooth Muscle

open access: yesThe FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Our previous study demonstrated that elevated levels of desmin and vimentin reduce BSM contractility. This study shows that the reduced BSM contractility is associated with mitochondrial impairment. G0/G1 switch gene 2 (G0S2) is upregulated in desmin‐ and vimentin‐overexpressing BSM.
Elham Javed   +21 more
wiley   +1 more source

Image Spam Filters Based on Optical Character Recognition (OCR) Techniques

open access: yes
In 2003, the first image with the spam text inside was reported by Graham-Cumming. Later, this technique was utilized successfully by spammers, by sending image spam as MIME attachments instead of sending as simple image tags.

core   +1 more source

SRS/SBRT commissioning process with a hybrid beam data model in new preconfigured CyberKnife system

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 10, October 2026.
Abstract Background A new preconfigured CyberKnife system was introduced to improve the SRS/SBRT commissioning efficiency. The vendor provides a reference beam data set, termed “beam data model (BDM)”, and recommends its validation and combination with measurement data to develop a hybrid beam data model (h‐BDM).
Mikoto Tamura   +10 more
wiley   +1 more source

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