Results 61 to 70 of about 417,443 (317)
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Investigation of performance issues affecting optical circuit and packet switched WDM networks [PDF]
Optical switching represents the next step in the evolution of optical networks. This thesis describes work that was carried out to examine performance issues which can occur in two distinct varieties of optical switching networks.
Smyth, Frank
core
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
International audienceWe present an analytical proof of the equivalence of scanning near-field optical images of small objects obtained by two alternative operating modes: (1) scanning at a constant distance from the mean plane of the surface and ...
Carminati, Remi, Greffet, Jean-Jacques
core +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Zoom Long-Wave Infrared Constant Ground Resolution Imaging Optical System Design
Long-wave infrared (LWIR) airborne optical systems for ground imaging are widely utilized in applications such as ground reconnaissance, agricultural monitoring, counterterrorism, and other fields.
Zhiqiang Yang +6 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
The spatial sensitivity of an erbium doped optical fibre distributed feedback (DFB) laser to an external magnetic field is reported. Intrinsic birefringence of the laser cavity allows lasing in two orthogonal modes.
Yuan Yao +3 more
core +1 more source
Mode dispersion and delay characteristics of optical waveguides using equivalent TL circuits [PDF]
A new analysis leading to an exact and efficient algorithm is presented for calculating directly and without numerical differentiation the mode dispersion characteristics of cylindrical dielectric waveguides of arbitrary refractive-index profile. The new
Boucouvalas, Anthony C., Qian, Xin
core +1 more source

