Results 41 to 50 of about 369,372 (313)
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Selenium semiconductor core optical fibers
Phosphate glass-clad optical fibers containing selenium (Se) semiconductor core were fabricated using a molten core method. The cores were found to be amorphous as evidenced by X-ray diffraction and corroborated by Micro-Raman spectrum.
G. W. Tang +7 more
doaj +1 more source
Engineering multiphoton states for linear optics computation
Transformations achievable by linear optical components allow to generate the whole unitary group only when restricted to the one-photon subspace of a multimode Fock space.
P. Aniello +9 more
core +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Perovskite quantum dots (QDs) attracted a lot of attention recently due to their high light conversion efficiency, and high color purity. However, perovskite materials are sensitive to heat.
Zong-Tao Li +7 more
doaj +1 more source
Carbon Quantum Dots Based Chemosensor Array for Monitoring Multiple Metal Ions
The simultaneous identification of multiple metal ions in water has attracted enormous research interest in the past few decades. We herein describe a novel method for multiple metal ion detection using a carbon quantum dots (CQDs)-based chemosensor ...
Tianlei Qin +3 more
doaj +1 more source
Optical phase shifting with acousto-optic devices
A novel optical phase-shifting method based on a well-known acousto-optic interaction is proposed. By using a pair of acousto-optic modulators (AOMs) and properly aligning them, we construct an optical phase shifter that can directly control the phase of a collimated beam.
Li, Enbang +4 more
openaire +4 more sources
Faraday rotators using permanently magnetized ferrite materials are used to make quasi-optical isolators and circulators at millimeter wave and sub-millimeter wave frequencies that have far higher performance than their waveguide equivalents.
Goy, P +7 more
core +1 more source

