Results 31 to 40 of about 3,266,597 (259)

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

open access: yesMolecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani   +7 more
wiley   +1 more source

An accretion disc model for quasar optical variability

open access: yes, 2008
Some different correlations between optical-ultraviolet (UV) variability and other quasar properties, such as luminosity, black hole mass and rest-frame wavelength, were discovered.
Li, Shuang-Liang, Cao, Xinwu
core   +1 more source

Results of the Optical Downlink Experiment KIODO from OICETS Satellite to Optical Ground Station Oberpfaffenhofen (OGS-OP) [PDF]

open access: yes, 2007
Optical LEO downlinks from the Japanese OICETS to the optical ground station built by the German Aerospace Center (DLR) near Munich have been performed. This was the first optical LEO downlink on European grounds.
Perlot, Nicolas   +13 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Enhancing ROP plus form diagnosis: An automatic blood vessel segmentation approach for newborn fundus images

open access: yesResults in Engineering
Background: ROP Plus Form is an eye disease that can lead to blindness, and diagnosing it requires medical experts to manually examine the retinal condition. This task is challenging due to its subjective nature and poor image quality.
José Almeida   +7 more
doaj   +1 more source

4GOOD - Technology and prototype for a 4th-Generation Omni-purpose Optical Disc system

open access: yes, 2008
Digital optical data storage has become firmly established through CD, DVD and their derivatives. Future mobile and stationary multimedia applications demand for ever higher storage density, even beyond HD-DVD and Blu-ray Disc with 50 GB maximum storage ...
Martin Behringer   +31 more
core   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

The stability of automatic ball balancers [PDF]

open access: yes, 2005
One realisation of an automatic balancer uses two or more balls that are free to travel in a race, filled with a viscous fluid, at a fixed distance from the shaft centre.
Green, K   +3 more
core  

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