Results 61 to 70 of about 608,125 (335)

Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó, Igor Stevanovski, Germán Morís, Roger Collet‐Vidiella, Alba Segarra‐Casas, Lidia González‐Quereda, Benjamín Rodríguez‐Santiago, Pia Gallano, Rodrigo Alvarez, Ana Vesperinas, Rosa Blanco, Beatriz San‐Millán, Carmen Navarro, Isabel Illa, Gianina Ravenscroft, Ira W. Deveson, Eduard Gallardo, Montse Olivé   +17 more
wiley   +1 more source

Parity-time symmetry in wavelength space within a single spatial resonator

Nature Communications, 2020
Most conventional PT-symmetric systems contain two physically separated modes. Here the authors proposed a PT-symmetric microwave optoelectronic oscillator, where the gain and loss modes are confined in a single spatial resonator, resulting in an ...
Jiejun Zhang, Lingzhi Li, Guangying Wang, Xinhuan Feng, Bai-Ou Guan, Jianping Yao   +5 more
doaj   +1 more source

Central Dysmyelination in SSADH‐Deficient Humans and Mice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl   +11 more
wiley   +1 more source

Linear and nonlinear optical properties of carbon nanotube-coated single-mode optical fiber gratings [PDF]

, 2011
This paper was published in OPTICS LETTERS and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://dx.doi.org/10.1364/OL.36.002104.
Benoit Simard, Chan, Choi, Chow, Chow, Chow, Claudio J. Oton, Guillermo E. Villanueva, Jacques Albert, Jakubinek, Joaquín Matres, Kingston, Li-Yang Shao, Michael B. Jakubinek, Pere Pérez-Millán, Sakakibara, Set, Vallaitis   +17 more
core   +2 more sources

Two‐Year Follow‐Up of a Multidisciplinary Lifestyle Intervention for Rheumatoid Arthritis and Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective The Plants for Joints (PFJ) intervention, including a whole‐food plant‐based diet, exercise, and stress reduction, reduced signs and symptoms of rheumatoid arthritis (RA) or metabolic syndrome–associated hip or knee osteoarthritis (MSOA) compared to usual care.
Carlijn A. Wagenaar, Wendy Walrabenstein, Marike van der Leeden, Franktien Turkstra, Martijn Gerritsen, Jos W. R. Twisk, Maarten Boers, Martin van der Esch, Henriët van Middendorp, Peter J. M. Weijs, Dirkjan van Schaardenburg   +10 more
wiley   +1 more source

Enhanced Photon-Pair Generation Based on Thin-Film Lithium Niobate Doubly Resonant Photonic Crystal Cavity

Photonics
In this work, a doubly resonant photonic crystal (PhC) cavity is proposed to enhance second harmonic generation (SHG) efficiency and photon pair generation rate (PGR). Through the exploration of geometry parameters, a band-edge mode within the light cone
Jinmian Zhu, Fengli Liu, Fangheng Fu, Yuming Wei, Tiefeng Yang, Heyuan Guan, Huihui Lu   +6 more
doaj   +1 more source

Single and dual fiber nano-tip optical tweezers: trapping and analysis

, 2013
An original optical tweezers using one or two chemically etched fiber nano-tips is developed. We demonstrate optical trapping of 1 micrometer polystyrene spheres at optical powers down to 2 mW.
Decombe, Jean-Baptiste, Fick, Jochen, Huant, Serge   +2 more
core   +3 more sources

Generation of Arbitrary Frequency Chirps with a Fiber-Based Phase Modulator and Self-Injection-Locked Diode Laser [PDF]

, 2006
We present a novel technique for producing pulses of laser light whose frequency is arbitrarily chirped. The output from a diode laser is sent through a fiber-optical delay line containing a fiber-based electro-optical phase modulator. Upon emerging from
Bakos, Boggs, C. E. Rogers III, Gertsvolf, Greiner, J. A. Pechkis, J. L. Carini, Levin, Li, Liendenbaum, M. J. Wright, Merkel, Miao, Ménager, Ménager, P. L. Gould, Pietiläinen, Reibel, Reibel, Repasky, Ricci, Thévenaz, Troger, Watts, Weiner, Wright, Wright   +26 more
core   +2 more sources

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

Depressed clad hollow optical fiber with fundamental LP01 mode cut-off

, 2006
We propose a depressed clad hollow optical fiber with fundamental (LP01) mode cut-off suitable for high power short-wavelength, especially three-level, fiber laser operation by introducing highly wavelength dependent losses at longer wavelengths. The cut-
Codemard, C., Dupriez, P., Jeong, Y., Kim, J., Nilsson, J., Sahu, J., Soh, D.B.S., Yoo, S.   +7 more
core   +1 more source