Results 71 to 80 of about 855,719 (327)

Tracing optical force fields within graded-index media

open access: yesNew Journal of Physics, 2014
The mechanical interaction between light and graded index media (both isotropic and anisotropic) is presented from the geometrical optics (GO) perspective.
Alireza Akbarzadeh   +3 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Quantum levitation by left-handed metamaterials [PDF]

open access: yes, 2007
Left-handed metamaterials make perfect lenses that image classical electromagnetic fields with significantly higher resolution than the diffraction limit. Here we consider the quantum physics of such devices.
Casimir H B G   +20 more
core   +6 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Fluctuation-induced forces on an atom near a photonic topological material

open access: yes, 2018
We theoretically study the Casimir-Polder force on an atom in a arbitrary initial state in a rather general electromagnetic environment wherein the materials may have a nonreciprocal bianisotropic dispersive response.
Antezza, Mauro   +3 more
core   +3 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Trapping and Optomechanical Sensing of Particles with a Nanobeam Photonic Crystal Cavity

open access: yesCrystals, 2019
Particle trapping and sensing serve as important tools for non-invasive studies of individual molecule or cell in bio-photonics. For such applications, it is required that the optical power to trap and detect particles is as low as possible, since large ...
Lin Ren, Yunpeng Li, Na Li, Chao Chen
doaj   +1 more source

Optical geometry analysis of the electromagnetic self-force

open access: yes, 2005
We present an analysis of the behaviour of the electromagnetic self-force for charged particles in a conformally static spacetime, interpreting the results with the help of optical geometry.
Marek A. Abramowicz   +2 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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