Results 41 to 50 of about 661,323 (302)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The design and development of a solar tracking unit [PDF]
The solar tracking unit was developed to support the Laser Heterodyne Spectrometer (LHS) airborne instrument, but has application to a general class of airborne solar occultation research instruments. The unit consists of a mirror mounted on two gimbals,
Jones, I. W., Miller, J. B.
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Light-driven soft robot with compound motion patterns based on gas–liquid phase transition chamber
Light is increasingly being used to drive soft robots and soft actuators. In this paper, a light-driven soft robot with compound motion patterns based on gas-liquid phase transition chamber is proposed, which inspired by the frog and the larvae of gall ...
Zheqi Zhou +7 more
doaj +1 more source
An exciting prospect for the sensing community is the potential of midinfrared fiber sensors. Taking advantage of the design flexibility of photonic crystal fiber and the high excitation loss of gold layers, a high-performance midinfrared D-shaped sensor
Nan Chen +4 more
doaj +1 more source
A device used in the optical alignment of machinery to maintain a measuring scale in the proper position for optical readings to be taken is described.
Mann, C. W.
core +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
A polarization beam splitter is an important component of modern optical system, especially a splitter that combines the structural flexibility of photonic crystal fiber and the optical modulation of functional material.
Nan Chen +5 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source

