Results 41 to 50 of about 661,323 (302)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The design and development of a solar tracking unit [PDF]

open access: yes, 1984
The solar tracking unit was developed to support the Laser Heterodyne Spectrometer (LHS) airborne instrument, but has application to a general class of airborne solar occultation research instruments. The unit consists of a mirror mounted on two gimbals,
Jones, I. W., Miller, J. B.
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Light-driven soft robot with compound motion patterns based on gas–liquid phase transition chamber

open access: yesScientific Reports
Light is increasingly being used to drive soft robots and soft actuators. In this paper, a light-driven soft robot with compound motion patterns based on gas-liquid phase transition chamber is proposed, which inspired by the frog and the larvae of gall ...
Zheqi Zhou   +7 more
doaj   +1 more source

Numerical Analysis of Midinfrared D-Shaped Photonic-Crystal-Fiber Sensor Based on Surface-Plasmon-Resonance Effect for Environmental Monitoring

open access: yesApplied Sciences, 2020
An exciting prospect for the sensing community is the potential of midinfrared fiber sensors. Taking advantage of the design flexibility of photonic crystal fiber and the high excitation loss of gold layers, a high-performance midinfrared D-shaped sensor
Nan Chen   +4 more
doaj   +1 more source

Rotary target V-block [PDF]

open access: yes, 1984
A device used in the optical alignment of machinery to maintain a measuring scale in the proper position for optical readings to be taken is described.
Mann, C. W.
core   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Numerical Investigation of a Short Polarization Beam Splitter Based on Dual-Core Photonic Crystal Fiber with As2S3 Layer

open access: yesMicromachines, 2020
A polarization beam splitter is an important component of modern optical system, especially a splitter that combines the structural flexibility of photonic crystal fiber and the optical modulation of functional material.
Nan Chen   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy