Results 31 to 40 of about 8,145 (310)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Polymer multimode waveguide optical and electronic PCB manufacturing

open access: yes, 2009
The paper describes the research in the £1.3 million IeMRC Integrated Optical and Electronic Interconnect PCB Manufacturing (OPCB) Flagship Project in which 8 companies and 3 universities carry out collaborative research and which was formed and is ...
Selviah, D.R., David R. Selviah
core   +1 more source

Stability, Causality, and Passivity in Electrical Interconnect Models [PDF]

open access: yes, 2007
Modern packaging design requires extensive signal integrity simulations in order to assess the electrical performance of the system. The feasibility of such simulations is granted only when accurate and efficient models are available for all system parts
ACHAR R.   +7 more
core   +1 more source

MRONoC: A Low Latency and Energy Efficient on Chip Optical Interconnect Architecture

open access: yesIEEE Photonics Journal, 2017
The circuit switched optical network on chip (ONoC) is popularly employed since the optical buffer is not available. However, this technique suffers from limited transmission bandwidth, high setup-time overhead, and high network resource contention ...
Huaxi Gu   +4 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Time domain response of corrugated transmission lines

open access: yesIET Microwaves, Antennas & Propagation
In order to employ periodic corrugated microstrip lines for reducing or suppressing electromagnetic interference in high‐speed or high‐frequency circuits, a precise method is necessary to calculate and measure the characteristic impedance of periodic ...
Chia Ho Wu   +10 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Theoretical investigation of a low-voltage Ge/SiGe multiple quantum wells optical modulator operating at 1310 nm integrated with Si3N4 waveguides

open access: yesAIP Advances, 2018
We report on the design and simulation using 3D-FDTD simulation of Si3N4-integrated Ge/SiGe multiple quantum wells (MQWs) optical modulators at the optical wavelength of 1310 nm.
Papichaya Chaisakul   +2 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Highly scalable OTDM router using computer controlled time slot tuner with picosecond resolution

open access: yes, 1999
An optical time division multiplexing (OTDM) router, using a highly scalable time slot tuner, is discussed. Channel access in OTDM networks is achieved by using time slot tuners and all-optical demultiplexers. Timing precision of
Glesk, Ivan   +8 more
core   +1 more source

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