Results 61 to 70 of about 4,177,043 (382)

Label-free optical biosensing with slot-waveguides [PDF]

Optics Letters, 2008
We demonstrate label-free molecule detection by using an integrated biosensor based on a Si(3)N(4)/SiO(2) slot-waveguide microring resonator. Bovine serum albumin (BSA) and anti-BSA molecular binding events on the sensor surface are monitored through the measurement of resonant wavelength shifts with varying biomolecule concentrations.
Angulo Barrios, Carlos, Bañuls, María José, González-Pedro, Victoria, Gylfason, Kristinn B., Sánchez, Benito, Griol Barres, Amadeu, Maquieira, A., Sohlström, Hans, Holgado Bolaños, Miguel, Casquel del Campo, Rafael   +9 more
openaire   +3 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Biophotonic Tools in Cell and Tissue Diagnostics. [PDF]

, 2007
In order to maintain the rapid advance of biophotonics in the U.S. and enhance our competitiveness worldwide, key measurement tools must be in place. As part of a wide-reaching effort to improve the U.S.
Brownstein, Michael, Dowell, ML, Gaigalas, AK, Hoffman, Robert A, Hwang, JC, Levenson, Richard, Milner, Thomas E, White, GS, Williams, PA   +8 more
core   +2 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Single-molecule mechanics of protein-labelled DNA handles

Beilstein Journal of Nanotechnology, 2016
DNA handles are often used as spacers and linkers in single-molecule experiments to isolate and tether RNAs, proteins, enzymes and ribozymes, amongst other biomolecules, between surface-modified beads for nanomechanical investigations. Custom DNA handles
Vivek S. Jadhav, Dorothea Brüggemann, Florian Wruck, Martin Hegner   +3 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

CONTROL SYSTEMS FOR CURRENT OPTICAL NETWORKS BASED ON GMPLS PROTOCOL

Revista Ingeniería, Matemáticas y Ciencias de la Información, 2017
Optical transport systems have evolved in many senses with the pass of years. A first advance can be seen on the transport network, which at the beginning used TDM protocol for transport.
CAROLINA VÁSQUEZ
doaj   +1 more source

Multiple Object Tracking in Urban Traffic Scenes with a Multiclass Object Detector

, 2018
Multiple object tracking (MOT) in urban traffic aims to produce the trajectories of the different road users that move across the field of view with different directions and speeds and that can have varying appearances and sizes.
B Coifman, HW Kuhn, J-P Jodoin, K Bernardin, Luis M. Fuentes, PF Felzenszwalb, RE Kalman, S Aslani   +7 more
core   +1 more source

Effects of crosstalk in WDM optical label switching networks due to wavelength switching of a tunable laser [PDF]

, 2006
rosstalk caused by switching events in fast tunable lasers in an optical label switching (OLS) system is investigated for the first time. A wavelength-division-multiplexed OLS system based on subcarrier multiplexed labels is presented which employs a 40 ...
Barry, Liam P., Connolly, Eoin M., Cotter, D., Ellis, A.D., Kaszubowska-Anandarajah, Aleksandra, Mishra, A.K., Smyth, Frank   +6 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source