Results 71 to 80 of about 216,176 (317)
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source
Single-molecule mechanics of protein-labelled DNA handles
Beilstein Journal of Nanotechnology, 2016 DNA handles are often used as spacers and linkers in single-molecule experiments to isolate and tether RNAs, proteins, enzymes and ribozymes, amongst other biomolecules, between surface-modified beads for nanomechanical investigations. Custom DNA handles
Vivek S. Jadhav +3 more
doaj +1 more source
Brucella NyxA and NyxB dimerization enhances effector function during infection
FEBS Letters, EarlyView.Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre +4 more
wiley +1 more source
FEBS Letters, EarlyView.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source
CONTROL SYSTEMS FOR CURRENT OPTICAL NETWORKS BASED ON GMPLS PROTOCOL
Revista Ingeniería, Matemáticas y Ciencias de la Información, 2017 Optical transport systems have evolved in many senses with the pass of years. A first advance can be seen on the transport network, which at the beginning used TDM protocol for transport.
CAROLINA VÁSQUEZ
doaj +1 more source
Advanced Photonics Research, 2022 The need to sense and track in real time through sustainable and multifunctional labels is exacerbated by the COVID‐19 pandemic, where the simultaneous measurement of body temperature and the fast tracking of people is required. One of the big challenges
João F. C. B. Ramalho +7 more
doaj +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Denoising Across Data Acquisition Modalities for Mesoscopic Scale Optical Neuroimaging
IEEE Access, 2021 The ever-evolving mesoscopic scale optical imaging systems facilitate the new discoveries in the neuroscience research. They excel at providing a complete view of the long projections of a single neuron across the whole brain.
Tianfang Zhu +5 more
doaj +1 more source
, 2019 We address the problem of video representation learning without human-annotated labels. While previous efforts address the problem by designing novel self-supervised tasks using video data, the learned features are merely on a frame-by-frame basis, which
Bao, Linchao +5 more
core +2 more sources
FEBS Letters, EarlyView.Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel +2 more
wiley +1 more source