Results 111 to 120 of about 204,940 (296)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Optical limiting in fullerene materials

, 1997
Fullerene chemistry is booming, but how the chemical reactions affect fullerene's materials properties has seldom been studied. We have investigated optical limiting behavior of a series of fullerene derivatives, polymers, and glasses and have observed ...
Peng, H., Leung, S. M., Tang, B. Z., Yu, N. T., Hiraoka, H., Fok, M. W.   +5 more
core   +1 more source

Optical Limiting Properties of DNA Biopolymer Doped with Natural Dyes. [PDF]

Polymers (Basel), 2023
Gheorghe P, Petris A, Anton AM.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Design of near-infrared dyes for nonlinear optics: toward optical limiting applications at telecommunication wavelengths

, 2009
International audienceThe rapid development of frequency-tunable pulsed lasers up to telecommunication wavelengths (1400-1600 nm) led to the design of new materials for nonlinear absorption in this spectral range.
Kamada, K., Bouit, P. -A, Bouit, Pierre-Antoine, Maury, Olivier, Kamada, Kenji, Andraud, C., Malmström, E., Malmström, Eva,, Bellier, Q., Feneyrou, P., Andraud, Chantal, Feneyrou, Patrick, Maury, O., Bellier, Quentin   +13 more
core   +1 more source

Investigation of the Defect and Intensity-Dependent Optical Limiting Performance of MnO₂ Nanoparticle-Filled Polyvinylpyrrolidone Composite Nanofibers. [PDF]

ACS Omega, 2023
Pepe Y, Akkoyun S, Asci N, Cevik E, Tutel Y, Karatay A, Unalan HE, Elmali A.   +7 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Metalloporphyrin polymer with temporally agile, broadband nonlinear absorption for optical limiting in the near infrared.

, 2009
A lead bis(ethynyl)porphyrin polymer possesses strong nonlinear absorption with unprecedented spectral/temporal coverage as a result of broad, overlapping two-photon and excited-state absorption bands with favorable excited-state dynamics.
Perry, JW, Hales, Joel M., Perry, Joseph W., Cozzuol, M, Cozzuol, Matteo, Anderson, Harry, Anderson, Harry L., Anderson, HL, Hales, JM, Screen, Thomas E. O., Screen, TE   +10 more
core   +1 more source