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Optical Genome Mapping for Oncology Applications

Current Protocols, 2023
AbstractOptical genome mapping (OGM) is a next‐generation cytogenomic technology that has the potential to replace standard‐of‐care technologies used in the genetic workup of various malignancies. The ability to detect various classes of structural variations that include copy number variations, deletions, duplications, balanced and unbalanced events ...
Nikhil Shri, Sahajpal   +4 more
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Mapping cone photopigment optical density

Journal of the Optical Society of America A, 1993
The distribution of cone photopigment across the retina affects the amount of light captured by cones at each retinal location. Cone photopigment optical density is measured in two ways, with reflectometry and/or with color matching. Color matching measures a higher optical density than does reflectometry.
A E, Elsner, S A, Burns, R H, Webb
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Optical Filtering of Aeromagnetic Maps

Applied Optics, 1974
An optical processor has been used to filter aeromagnetic contour maps in order to obtain information on underground magnetic ore deposits. This was accomplished by directional filtering of the spatial Fourier transform of the contour map. The directional filtering yields maps of gradients having given directions.
H H, Arsenault   +2 more
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Optical map transformations

Optics Communications, 1974
Abstract An optical technique for performing general types of map transformations is introduced. Using a coherent system, the object distribution is multiplied by a phase function so that its frequency spectrum constitutes the transformation wanted. Also shown is how imaging systems can be made space variant.
openaire   +1 more source

Potential mapping of optical tweezers

Optics Letters, 2011
Optical tweezers are very often used for measurement of piconewton range forces. Depending on the displacement of the trapped bead, the trap may become stiffer which causes considerable underestimation of the measured force. We have shown, both by theory and experiment, that such a stiffening occurs for beads larger than 0.5 μm in radius. For the first
Tahmineh, Godazgar   +2 more
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Genomics via Optical Mapping II: Ordered Restriction Maps

Journal of Computational Biology, 1997
In this paper, we describe our algorithmic approach to constructing ordered restriction maps based on the data created from the images of population of individual DNA molecules (clones) digested by restriction enzymes. The goal is to devise map-making algorithms capable of producing high-resolution, high-accuracy maps rapidly and in a scalable manner ...
T S, Anantharaman   +2 more
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Optical field mapping using single-mode optical fibers

Applied Optics, 1978
A new method of measuring the complete optical field distribution (optical field mapping) is proposed and is applied to the measurement of Gaussian beam distribution at its beam waist. This method utilizes an interference technique and uses two single-mode optical fibers as flexible paths.
M, Liyama, T, Kamiya, H, Yanai
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Optical Mapping Applications

SPIE Proceedings, 1988
Holography can be used for arbitrary, parallel, weighted mappings between planes with up to to 106 pixels each at I/O limited rates. This allows precalculated mappings to occur at very high speed. The applicarttions for one-to-one, one-to-many, many-to-one, and many-to-many maps are explored here.
openaire   +1 more source

Coherent Optics in Mapping

Optical Engineering, 1975
Several potential applications of coherent optics in the field of topographic mapping have been identified.1 This paper outlines the motivation for applying coherent optics to topographic mapping, presents some additional applications not included in Ref. 1, and further discusses some applications developed in that reference.
N. Balasubramanian, R. D. Leighty
openaire   +1 more source

Towards low cost, deep water AUV optical mapping

OCEANS 2018 MTS/IEEE Charleston, 2018
The high cost associated with autonomous underwater vehicles (AUVs) capable of operating beyond the mesopelagic ocean zone has prevented the extensive study of the deep ocean. Consequently, little is known about these regions deeper than 1000 m. However,
Eduardo Iscar   +3 more
semanticscholar   +1 more source

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