Results 61 to 70 of about 1,684,231 (305)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Predicting Scattering Scanning Near-field Optical Microscopy of Mass-produced Plasmonic Devices

, 2018
Scattering scanning near-field optical microscopy enables optical imaging and characterization of plasmonic devices with nanometer-scale resolution well below the diffraction limit.
Ashby, Paul D., Burgos, Stanley P., Hammack, Aeron T., Otto, Lauren M., Ren, Shen, Staffaroni, Matteo, Stipe, Barry C., Suzer, Ozgun   +7 more
core   +1 more source

Statistical uncertainty in quantum optical photodetection measurements [PDF]

, 1998
We present a complete statistical analysis of quantum optical measurement schemes based on photodetection. Statistical distributions of quantum observables determined from a finite number of experimental runs are characterized with the help of the ...
Banaszek K., Eadie W. T., Jacobs K., Konrad Banaszek, Tan S. M., Vogel W.   +5 more
core   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Deep Learning in Cardiovascular Tissue Engineering: A Review on Current Advances and Future Perspectives

Technologies
The development of cardiovascular tissue engineering is a promising area of study in regenerative medicine, offering innovative solutions for restoring damaged cardiac structures.
Dumitru-Daniel Bonciog, Adriana Berdich, Liliana Mâțiu-Iovan, Valentin Laurențiu Ordodi   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

On Possibility of Detonation Products Temperature Measurements of Emulsion Explosives

Archives of Metallurgy and Materials, 2014
The new view on the structure of the radiance signal recorded by optical pyrometer and the preliminary results of brightness detonation temperature of the emulsion explosive are presented.
Silvestrov V. V., Bordzilovskii S. A., Karakhanov S. M., Plastinin A. V.   +3 more
doaj   +1 more source

Full microscopic treatment of the optical response of the Si(100)2x1 surface [PDF]

, 1993
The optical reflection from the Si(100) 2 × 1 surface has been calculated, using the discrete dipole model and local polarizabilities obtained from quantum mechanical cluster calculations.
Bekker, H.G., Boeij, P.L. de, Poppe, G.P.M., Wentink, D.J., Wijers, C.M.J.   +4 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source