Results 41 to 50 of about 888,059 (303)

Cavity-enhanced optical detection of carbon nanotube Brownian motion [PDF]

, 2012
Optical cavities with small mode volume are well-suited to detect the vibration of sub-wavelength sized objects. Here we employ a fiber-based, high-finesse optical microcavity to detect the Brownian motion of a freely suspended carbon nanotube at room ...
D. Hunger, E. M. Weig, I. Favero, J. Reichel, L. Ost, S. Stapfner, Weaver W.   +6 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A simplified version of rapid susceptibility testing of bacteria and yeasts using optical nanomotion detection

Frontiers in Microbiology
We present a novel optical nanomotion-based rapid antibiotic and antifungal susceptibility test. The technique consisted of studying the effects of antibiotics or antifungals on the nanometric scale displacements of bacteria or yeasts to assess their ...
Maria I. Villalba, Maria I. Villalba, Vojislav Gligorovski, Sahand J. Rahi, Ronnie G. Willaert, Ronnie G. Willaert, Sandor Kasas, Sandor Kasas, Sandor Kasas   +8 more
doaj   +1 more source

Electron microscopic measurement of the size of the optical focus in laser scanning microscopy [PDF]

, 2012
We describe a method for measuring the lateral focal spot size of a multiphoton laser scanning microscope (LSM) with unprecedented accuracy. A specimen consisting of an aluminum film deposited on a glass coverslip was brought into focus in a LSM and the ...
Alison McDonald, Ditchburn, Gail McConnell, Inoué, Siegman, William B. Amos   +5 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Development of Projection Optical Microscopy and Direct Observation of Various Nanoparticles

Optics
The optical microscope is an indispensable observation instrument that has fundamentally contributed to progress in science and technology. Dark-field microscopy and scattered light imaging techniques enable high-contrast observation of nanoparticles in ...
Toshihiko Ogura
doaj   +1 more source

Water window imaging x ray microscope [PDF]

, 1992
A high resolution x ray microscope for imaging microscopic structures within biological specimens has an optical system including a highly polished primary and secondary mirror coated with identical multilayer coatings, the mirrors acting at normal ...
Hoover, Richard B.
core   +1 more source

How to erase surface plasmon fringes

, 2010
We report the realization of a dual surface plasmon polariton (SPP) microscope based on leakage radiation (LR) analysis. The microscope can either image SPP propagation in the direct space or tin the Fourier space.
Alfred Leitner, Andreas Hohenau, Andrey L. Stepanov, Aurelien Drezet, Bernhard Steinberger, Franz R. Aussenegg, Harald Ditlbacher, Joachim R. Krenn, Nicole Galler, Raether H.   +9 more
core   +1 more source

Design and characterization of dielectric filled TM$_{110}$ microwave cavities for ultrafast electron microscopy [PDF]

, 2018
Microwave cavities oscillating in the TM$_{110}$ mode can be used as dynamic electron-optical elements inside an electron microscope. By filling the cavity with a dielectric material it becomes more compact and power efficient, facilitating the ...
A. H. Kemper, Collin R. E., E. H. Rietman, E. R. Kieft, Griffiths D. J., H. A. van Doorn, I. Koole, J. F. M. van Rens, O. J. Luiten, P. H. A. Mutsaers, Pozar D. M., W. Verhoeven   +11 more
core   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source