Results 71 to 80 of about 4,795,126 (305)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Nano-scale characterization of iron-carbohydrate complexes by cryogenic scanning transmission electron microscopy: Building the bridge to biorelevant characterization

Heliyon
Iron deficiency and iron deficiency anemia pose significant health challenges worldwide. Iron carbohydrate nanoparticles administered intravenously are a mainstay of treatment to deliver elemental iron safely and effectively.
Reinaldo Digigow, Michael Burgert, Marco Luechinger, Alla Sologubenko, Andrzej J. Rzepiela, Stephan Handschin, Amy E. Barton Alston, Beat Flühmann, Erik Philipp   +8 more
doaj   +1 more source

Characterization methods dedicated to nanometer-thick hBN layers

, 2016
Hexagonal boron nitride (hBN) regains interest as a strategic component in graphene engineering and in van der Waals heterostructures built with two dimensional materials.
Barjon, Julien, Fossard, Frederic, Loiseau, Annick, Schue, Leonard, Stenger, Ingrid   +4 more
core   +3 more sources

Wide-field optical sectioning for live-tissue imaging by plane-projection multiphoton microscopy [PDF]

, 2011
Optical sectioning provides three-dimensional (3D) information in biological tissues. However, most imaging techniques implemented with optical sectioning are either slow or deleterious to live tissues.
Blake, Geoffrey A., Chen, Yenyu, Guo, Chin-Lin, Holland, Daniel B., Kuo, Chun-Hung, Ouyang, Mingxing, Yu, Jiun-Yann, Zadoyan, Ruben   +7 more
core   +1 more source

Plasmon‐Tunable Tip Pyramids: Monopole Nanoantennas for Near‐Field Scanning Optical Microscopy

Advanced Optical Materials, 2018
Squeezing optical fields into nanometer scale is the key step to perform spatially resolved near‐field optics. In scattering‐type near‐field optical microscopy, this task is accomplished by nanoantennas that convert propagating radiation to local near ...
T. Vasconcelos, B. Archanjo, B. S. Oliveira, R. Valaski, Rafael C. Cordeiro, Helton G Medeiros, Cassiano Rabelo, Aroldo Ribeiro, P. Ercius, C. Achete, A. Jorio, L. G. Cançado   +11 more
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

High-resolution 3D optical microscopy inside the beating zebrafish heart using prospective optical gating [PDF]

, 2012
3D fluorescence imaging is a fundamental tool in the study of functional and developmental biology, but effective imaging is particularly difficult in moving structures such as the beating heart.
Girkin, J.M., Love, G.D., Taylor, J.M.
core   +1 more source

Non-Ising and chiral ferroelectric domain walls revealed by nonlinear optical microscopy

Nature Communications, 2017
The properties of ferroelectric domain walls can significantly differ from those of their parent material. Elucidating their internal structure is essential for the design of advanced devices exploiting nanoscale ferroicity and such localized functional ...
S. Cherifi‐Hertel, H. Bulou, R. Hertel, G. Taupier, K. Dorkenoo, C. Andreas, J. Guyonnet, I. Gaponenko, K. Gallo, P. Paruch   +9 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Isolation and characterization of few-layer black phosphorus [PDF]

, 2014
Isolation and characterization of mechanically exfoliated black phosphorus flakes with a thickness down to two single-layers is presented. A modification of the mechanical exfoliation method, which provides higher yield of atomically thin flakes than ...
Alvarez, J. V., Blanter, Sofya I., Buscema, Michele, Castellanos-Gomez, Andres, Groenendijk, Dirk J., Island, Joshua O., Narasimha-Acharya, K. L., Palacios, J. J., Prada, Elsa, Steele, Gary A., van der Zant, Herre S. J., Vicarelli, Leonardo, Zandbergen, Henny W.   +12 more
core   +2 more sources