Results 81 to 90 of about 4,795,126 (305)
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Three-dimensional Optical-resolution Photoacoustic Microscopy [PDF]
, 2011 Optical microscopy, providing valuable insights at the cellular and organelle levels, has been widely recognized as an enabling biomedical technology.
B. Rao +23 more
core +1 more source
All-digital histopathology by infrared-optical hybrid microscopy
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance This study reports the ability to provide label-free molecular information from infrared (IR) spectroscopy via the ubiquitous optical microscope.
M. Schnell +8 more
semanticscholar +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Detection of weak optical absorption by optical-resolution photoacoustic microscopy
Photoacoustics, 2022 Optical-resolution photoacoustic microscopy (OR-PAM) is one of the major implementations of photoacoustic (PA) imaging. With tightly focused optical illumination and high-frequency ultrasound detection, OR-PAM provides micrometer-level resolutions as ...
Tingyang Duan +5 more
doaj +1 more source
Remote optical addressing of single nano-objects [PDF]
, 2003 We present a scheme for remotely addressing single nano-objects by means of near-field optical microscopy that makes only use of one of the most fundamental properties of electromagnetic radiation: its polarization.
A Drezet +10 more
core +3 more sources
Photothermal Microscopy: Imaging the Optical Absorption of Single Nanoparticles and Single Molecules
ACS Nano, 2020 The photothermal (PT) signal arises from slight changes of the index of refraction in a sample due to absorption of a heating light beam. Refractive index changes are measured with a second probing beam, usually of a different color.
S. Adhikari +5 more
semanticscholar +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Multimodal nonlinear optical microscopy [PDF]
Laser & Photonics Reviews, 2011 AbstractBecause each nonlinear optical (NLO) imaging modality is sensitive to specific molecules or structures, multimodal NLO imaging capitalizes the potential of NLO microscopy for studies of complex biological tissues. The coupling of multiphoton fluorescence, second‐harmonic generation, and coherent anti‐Stokes Raman scattering (CARS) has allowed ...
Shuhua, Yue +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source