Results 101 to 110 of about 579,349 (293)

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Significantly High Modulation Efficiency of Compact Graphene Modulator Based on Silicon Waveguide

Scientific Reports, 2018
We theoretically and experimentally demonstrate a significantly large modulation efficiency of a compact graphene modulator based on a silicon waveguide using the electro refractive effect of graphene.
Haowen Shu, Zhaotang Su, Le Huang, Zhennan Wu, Xingjun Wang, Zhiyong Zhang, Zhiping Zhou   +6 more
doaj   +1 more source

Evaluation of a discrete 4-PAM optical link for future automotive networks [PDF]

, 2012
A comparative study is presented between NRZ and 4-PAM to investigate the feasibility of Gigabit transmission in automotive optical networks. The system utilizes a SI-PCS fiber and an 850 nm VCSEL as transmitter.
Bauwelinck, Johan, Soenen, Wouter, Vaernewyck, Renato   +2 more
core  

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

High-coherence parallelization in integrated photonics

Nature Communications
Coherent optics has profoundly impacted diverse applications ranging from communications, LiDAR to quantum computations. However, developing coherent systems in integrated photonics comes at great expense in hardware integration and energy efficiency ...
Xuguang Zhang, Zixuan Zhou, Yijun Guo, Minxue Zhuang, Warren Jin, Bitao Shen, Yujun Chen, Jiahui Huang, Zihan Tao, Ming Jin, Ruixuan Chen, Zhangfeng Ge, Zhou Fang, Ning Zhang, Yadong Liu, Pengfei Cai, Weiwei Hu, Haowen Shu, Dong Pan, John E. Bowers, Xingjun Wang, Lin Chang   +21 more
doaj   +1 more source

Flexible Baseband-Unit Aggregation Enabled by Reconfigurable Multi-IF Over WDM Fronthaul

IEEE Photonics Journal, 2018
In cloud-radio access network, baseband-unit (BBU) aggregation schemes have been intensively discussed to improve the efficiency of resources in light traffic times.
Haiyun Xin, Hao He, Kuo Zhang, Syed Baqar Hussain, Weisheng Hu   +4 more
doaj   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Wide-area remote-sensing system of pollution and gas dispersal by near-infrared absorption based on low-loss optical fiber network [PDF]

, 1986
An all optical remote sensing system utilizing long distance, ultralow loss optical fiber networks is studied and discussed for near infrared absorption measurements of combustible and/or explosive gases such as CH4 and C3H8 in our environment, including
Inaba, H.
core   +1 more source