Results 41 to 50 of about 42,810 (293)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Efficient and spectrally bright source of polarization-entangled photons

, 2004
We demonstrate an efficient fiber-coupled source of nondegenerate polarization entangled photons at 795 and 1609 nm using bidirectionally pumped parametric down-conversion in bulk periodically poled lithium niobate. The single-mode source has an inferred
Albota, Marius A., König, Friedrich, Mason, Elliott J., Wong, Franco N. C.   +3 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

55% Efficient High-Power Multijunction Photovoltaic Laser Power Converters for 1070 nm

Photonics
High-efficiency multijunction laser power converters are demonstrated for the first time at high power for optical inputs around 1070 nm. The InP-based photovoltaic power-converting III–V heterostructures are designed with eight lattice-matched InGaAsP ...
Simon Fafard, Denis Masson
doaj   +1 more source

Compact, low power and low threshold electrically pumped micro disc lasers for 20Gb/s non return to zero all optical wavelength conversion [PDF]

, 2010
\u3cp\u3eUsing a 7.5μm wide InP Micro-Disc-Laser, with a very low ∼100μA threshold current, heterogeneously integrated on top of Silicon on Insulator substrate, all optical NRZ wavelength conversion at speeds up to 20Gb/s is demonstrated.\u3c/p ...
de Vries, T, Dorren, HJS, Kumar, Rajesh, Liu, L, Morthier, Geert, Raz, O, Regreny, P, Rojo-Romeo, P, Van Thourhout, Dries   +8 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Measurement of the stimulated carrier lifetime in semiconductor optical amplifiers by four-wave mixing of polarized ASE noise [PDF]

, 1997
We present a simple experiment aimed at measuring the stimulated carrier lifetime in semiconductor optical amplifiers (SOA's). The technique relies on polarization-resolved nearly degenerate four-wave mixing (FWM) of a laser source with an amplified ...
Hunziker, Guido, Koren, Uzi, Paiella, Roberto, Vahala, Kerry J.   +3 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Recent Advances in Coherent Optical Communications for Short-Reach: Phase Retrieval Methods

Photonics, 2023
Short-reach transmission systems traditionally utilize intensity modulation (IM) at the transmitter and direct detection (DD) at the receiver due to their cost-effectiveness, small footprint, and low power consumption.
Abdullah S. Karar, Abdul Rahman El Falou, Julien Moussa H. Barakat, Zeynep Nilhan Gürkan, Kangping Zhong   +4 more
doaj   +1 more source