Results 21 to 30 of about 40,705 (261)

A 42.7Gb/s Optical Receiver With Digital Clock and Data Recovery in 28nm CMOS

open access: yesIEEE Access
This paper presents a broadband optical receiver that employs multiple bandwidth extension techniques in analog front-end (AFE) and has efficient digital clock and data recovery (CDR). The AFE is implemented exclusively with inverter-based stages.
Hyungryul Kang   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Integrated optical vortex beam receivers [PDF]

open access: yesOptics Express, 2016
A simple and ultra-compact integrated optical vortex beam receiver device is presented. The device is based on the coupling between the optical vortex modes and whispering gallery modes in a micro-ring resonator via embedded angular gratings, which provides the selective reception of optical vortex modes with definitive total angular momentum ...
Cicek, Kenan   +11 more
openaire   +6 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

A DSP-free carrier phase recovery system using 16-offset-QAM laser forwarded links for 400 Gb/s and beyond

open access: yesFrontiers in Communications and Networks
Optical interconnects are becoming a major bottleneck in scaling up future GPU racks and network switches within data centers. Although 200 Gb/s optical transceivers using PAM-4 modulation have been demonstrated, achieving higher data rates and energy ...
Marziyeh Rezaei   +3 more
doaj   +1 more source

Multi-Gain-Stage InGaAs Avalanche Photodiode With Enhanced Gain and Reduced Excess Noise

open access: yesIEEE Journal of the Electron Devices Society, 2013
We report the design, fabrication, and test of an InGaAs avalanche photodiode (APD) for 950–1650 nm wavelength sensing applications. The APD is grown by molecular beam epitaxy on InP substrates from lattice-matched InGaAs and InAlAs alloys ...
George M. Williams   +4 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Recent Advances of High-Speed Short-Reach Optical Interconnects for Data Centers

open access: yesIEEE Open Journal of the Solid-State Circuits Society
The ever-increasing demand for data centers and high-performance computing systems necessitate power-efficient, low-latency, and high-density interconnect design.
Chongyun Zhang   +4 more
doaj   +1 more source

Design and Analysis of Optical Receiving Antenna for LED Visible Light Communication Based on Taguchi Method

open access: yesIEEE Access, 2019
A scheme for designing a novel optical receiving antenna is proposed to extend the field of view, receive higher power, and reduce the received-energy spot area for indoor visible light communication (VLC).
Xing Peng   +3 more
doaj   +1 more source

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