Results 31 to 40 of about 40,705 (261)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Naponski izlazni signali poziciono-osetljivog optičkog prijemnika / The voltage output signals of the optical position-sensitive receiver

Vojnotehnički Glasnik, 2006
Teorijski model za određivanje naponskih izlaznih signala poziciono-osetljivog prijemnika razvijen je i eksperimentalno verifikovan. Upotrebljen je kvadrantni detektor za konvertovanje svetlosne energije u električnu energiju.
Željko Vukobrat
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

A −11.6-dBm OMA Sensitivity 0.55-pJ/bit 40-Gb/s Optical Receiver Designed Using a 2-Port-Parameter-Based Design Methodology

IEEE Open Journal of the Solid-State Circuits Society
This article presents a systematic design methodology for transimpedance amplifiers (TIAs) based on two-port parameters, enabling efficient exploration of complex TIA architectures, including multistage forward amplifiers, and facilitating the ...
Yongxin Li, Tianyu Wang, Mostafa Gamal Ahmed, Ruhao Xia, Kyu-Sang Park, Mahmoud A. Khalil, Sashank Krishnamurthy, Zhe Xuan, Ganesh Balamurugan, Pavan Kumar Hanumolu   +9 more
doaj   +1 more source

Research and Application of Quasi-Coherent Technology in C-Band 25 Gbit/s Optical Transceiver

Guangtongxin yanjiu, 2021
In order to extend the transmission distance of the traditional C-band high-speed optical module, this paper studies a kind of quasi-coherent reception technology based on the existing 25 Gbit/s optical module, and discusses the application scheme of the
Ling-qiao KONG, Qin-lian BU
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Free Space Optic Receiver with Strongly Overlapped Photodetectors’ Field of View

Applied Sciences, 2019
In this study, we designed a mobile free space optic receiver that uses several photodetectors to provide omnidirectional receiving capability. Assuming only one transmitter, it is a receiver which builds a single input multiple output optical channel ...
Karel Witas, Jan Nedoma
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Hybrid SPAD/PD Receiver for Reliable Free-Space Optical Communication

IEEE Open Journal of the Communications Society, 2020
Free-space optical (FSO) communication provides wireless optical connectivity with high data rates and low-cost implementation; however, its performance is strongly influenced by the power attenuation due to the infrequent adverse weather conditions ...
Shenjie Huang, Majid Safari
doaj   +1 more source

Integrated Components and Solutions for High-Speed Short-Reach Data Transmission

Photonics, 2021
According to different transmission distances, application scenarios of a data center mainly include intra- and inter-data center optical interconnects.
Lin Jiang, Lianshan Yan, Anlin Yi, Yan Pan, Bo Zhang, Qianggao Hu, Wei Pan, Bin Luo   +7 more
doaj   +1 more source