Results 51 to 60 of about 40,705 (261)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

INFLUENCE OF THE stimulated Brillouin scattering PREAMPLIFIER NOISE ON RECEIVING THE TRANSFORMED SPECTRUM SIGNALS

Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019
An analysis of the influence of preamplifier noise with effect of stimulated Brillouin scattering (SBS) in the SNR on receiving the transformed spectrum signals was presented in this paper.
V. N. Uryadov, Y. V. Roshchupkin, V. Y. Bunas, A. S. Zelenin   +3 more
doaj  

Low-Noise Modified-RGC Transimpedance Amplifier With Bandwidth Enhancement Using an Intrinsic Negative-RC Network

IEEE Access
This paper presents a dual feedback transimpedance amplifier (TIA) with a modified regulated-cascode (RGC) topology that employs a negative resistance-capacitance (NRC) network to enhance both bandwidth and noise performance.
Behnam Abdollahi, Baset Mesgari, Saeed Saeedi, Zahra Sohrabi, Horst Zimmermann   +4 more
doaj   +1 more source

Hybrid Microoptical WDM Receiver for PON Communication

Advances in Electrical and Electronic Engineering, 2012
The paper presents the design, simulation and construction results of the wavelength division multiplex (WDM) optical hybrid receiver module for the passive optical network (PON).
Vitezslav Jerabek, Julio Armas, Vaclav Prajzler   +2 more
doaj   +1 more source

Advanced optical receiver architectures for ultra-high capacity but low-cost short-reach optical interconnects

Dianxin kexue, 2022
The deployment of emerging network infrastructure such as hyper-scale datacenters urgently requires ultra-high capacity but low-cost short-reach optical interconnects.Conventional intensity modulation and direct detection possesses a simple receiver ...
Honglin JI, Xueyang LI, Zhixue HE, Weisheng HU, Shieh William   +4 more
doaj   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Cubic-Receiver-Based Indoor Optical Wireless Location System

IEEE Photonics Journal, 2016
A cubic-receiver-based indoor optical wireless location system is proposed in this paper. The cubic receiver arranging five photodiodes (PDs) as a cubic structure is used as photodetector to measure the angles of arrival (AOAs) of the incident light from
Ling Wei, Hongming Zhang, Bingyan Yu, Jian Song, Yang Guan   +4 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Ultra Sensitive PIN-Diode Receiver Utilizing Photocurrent Integration on a Parasitic Capacitance

IEEE Access
This work presents a highly sensitive monolithic optical receiver in $\mathrm {0.35~\mu m}$ CMOS. The integrator-based frontend employs periodic photocurrent integration on a parasitic capacitance in combination with an ultra-low-capacitance PIN ...
Christoph Gasser, Simon Michael Laube, Kerstin Schneider-Hornstein, Horst Zimmermann   +3 more
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source