Results 41 to 50 of about 70,027 (278)

Characterization of low-noise quasi-optical SIS mixers for the submillimeter band [PDF]

, 1996
We report on the development of low-noise quasi-optical SIS mixers for the frequency range 400-850 GHz. The mixers utilize twin-slot antennas, two-junction tuning circuits, and Nb-trilayer junctions. Fourier-transform spectrometry has been used to verify
Bin, Mei, Gaidis, Michael C., LeDuc, Henry G., Miller, David, Stern, Jeffrey A., Zmuidzinas, Jonas   +5 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

High-speed Si-Ge avalanche photodiodes

PhotoniX, 2022
High-speed optical interconnects of data centers and high performance computers (HPC) have become the rapid development direction in the field of optical communication owing to the explosive growth of market demand.
Binhao Wang, Jifang Mu
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Pilot-Assisted Phase Recovery in Coherent Optical Receivers with Robust Locally Weighted Interpolation

Photonics
Accurate and low-complexity phase estimation is crucial for optimal data recovery in coherent optical receivers, especially for applications in emerging scenarios such as low-margin optical networks, green networks, probabilistic-shaping modulation, the ...
Carlos Carrión Betancourt, Veruska Rodrigues Moreira, Kayol Soares Mayer, Jonathan Aguiar Soares, Dalton Soares Arantes   +4 more
doaj   +1 more source

Photonic-Assisted Receivers for Instantaneous Microwave Frequency Measurement Based on Discriminators of Resonance Type

Photonics, 2022
Photonic-assisted receivers for instantaneous microwave frequency measurement are devices used to measure the instantaneous frequency and amplitude of one or more microwave signals in the optical range, typically used in radar systems.
Alexander Ivanov, Oleg Morozov, Airat Sakhabutdinov, Artem Kuznetsov, Ilnur Nureev   +4 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Novel ring resonator-based integrated photonic beamformer for broadband phased array receive antennas - part I: design and performance analysis [PDF]

, 2010
A novel optical beamformer concept is introduced that can be used for seamless control of the reception angle in broadband wireless receivers employing a large phased array antenna (PAA).
Bentum, Mark J., Burla, Maurizio, Etten, Wim van, Huizinga, Adriaan, Jorna, Pieter, Marpaung, David A.I., Meijerink, Arjan, Meijerink, Roland, Roeloffzen, Chris G.H., Verpoorte, Jaco, Zhuang, Leimeng   +10 more
core   +3 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Ultracompact monolithic integration of balanced, polarization diversity photodetectors for coherent lightwave receivers [PDF]

, 1992
The authors have monolithically integrated an optical front-end on InP for balanced, polarization-diversity coherent lightwave reception which is only 1.3-mm long. Low on-chip insertion loss (
Andreadakis, N. C., Caneau, C., Curtis, L., Deri, R. J., Gozdz, A. S., Hawkins, R. J., Pennings, E. C. M., Scherer, A., Shah, V., Song, J.-I., Soole, J. B. D.   +10 more
core   +1 more source