Results 31 to 40 of about 109,372 (292)

Optics of rotating systems [PDF]

open access: yesPhysical Review A, 2009
Electrodynamics of rotating systems is expected to exhibit novel nonlocal features that come about when acceleration-induced nonlocality is introduced into the special relativity theory in conformity with the Bohr-Rosenfeld principle. The implications of nonlocality for the amplitude and frequency of electromagnetic radiation received by uniformly ...
openaire   +2 more sources

Protein Polarimetry, Perfected: Specific Rotation Measurement for the Refracto-Polarimetric Detection of Cryptic Protein Denaturation

open access: yesBiophysica
Protein polarimetry has been evaluated as a simple and straightforward technique to detect the cryptic denaturation of exemplary proteins. The general rules of rotation vs.
Lisa Riedlsperger   +3 more
doaj   +1 more source

Design and application of intelligent optical rotation detection and remote monitoring system

open access: yesDianzi Jishu Yingyong, 2018
An intelligent optical detection and remote monitoring system is designed based on the principle of physical optics. The system uses a microcontroller unit to control the polarizer movement, and uses the photosensitive sensor to detect the light ...
Zhang Zihao, Yang Hong, Chen Dan
doaj   +1 more source

Ultrasensitive Protein Concentration Characterization Based on Weak Measurements

open access: yesPhotonic Sensors, 2022
An optical rotation bio-sensor based on the photonic spin Hall effect was established and applied to detecting the concentration varieties of chiral molecules.
Bowen Song   +3 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Optical rotation of white light [PDF]

open access: yesAmerican Journal of Physics, 2020
Plane-polarized monochromatic light is rotated in an optically active medium. The extent of the rotation is wavelength dependent, following an optical rotatory dispersion (ORD) curve. Typically, this phenomenon is studied by using a few discrete wavelengths. Here, we demonstrate optical rotation of white light. Corn syrup is used as the medium as large
Anderson, Jason   +4 more
openaire   +3 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Determination of the Absolute Configurations of Chiral Drugs Using Chiroptical Spectroscopy

open access: yesMolecules, 2016
Chiroptical spectroscopy has emerged as a promising tool for the determination of absolute configurations and predominant conformations of chiral molecules in academic laboratories.
Prasad L. Polavarapu
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Bioactive Metabolites from Mangrove Endophytic Fungus Aspergillus sp. 16-5B

open access: yesMarine Drugs, 2015
Chemical investigation of the endophytic fungus Aspergillus sp. 16-5B cultured on Czapek’s medium led to the isolation of four new metabolites, aspergifuranone (1), isocoumarin derivatives (±) 2 and (±) 3, and (R)-3-demethylpurpurester A (4), together ...
Yayue Liu   +7 more
doaj   +1 more source

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