Results 91 to 100 of about 559,327 (258)

Tailoring the Anomalous Hall Effect in van der Waals Ferromagnet Fe3GeTe2

open access: yesTaiyuan Ligong Daxue xuebao
[Purposes] The intrinsic magnetic moments of magnetic materials can lead to anomalous Hall effects, and the Hall resistance can be significantly reduced, thus improving the heat loss in micro- and nanoelectronic devices.
WU Kaile   +6 more
doaj   +1 more source

Optical fibre nanowire sensors and applications

open access: yes, 2012
Optical fibre nanowires (OFN) have recently attracted increased attention because of their numerous applications in sensing and particle manipulation [1] and their extraordinary optical and mechanical properties, which include, amongst others ...
Brambilla, Gilberto, Ding, Ming
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Studies and development of FBG based multi-point temperature sensor for vacuum chambers of synchrotron radiation source Indus-2

open access: yesResults in Optics
This paper presents the development and deployment of a multi-point fiber Bragg grating (FBG) sensor system for precise temperature monitoring along the vacuum chamber walls of dipole and Pinger magnets in Indus-2, a synchrotron radiation source.
J. Kumar   +8 more
doaj   +1 more source

Status of the Fiber Optic Control System Integration (FOCSI) program [PDF]

open access: yes
This report presents a discussion of the progress made in the NASA/NAVY Fiber Optic Control System Integration (FOCSI) program. This program will culminate in open-loop flight tests of passive optical sensors and associated electro-optics on an F-18 ...
Baumbick, Robert J.
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Deep Integration of Fiber-Optic Communication and Sensing Systems Using Forward-Transmission Distributed Vibration Sensing and on–off Keying

open access: yesSensors
The deep integration of communication and sensing technology in fiber-optic systems has been highly sought after in recent years, with the aim of rapid and cost-effective large-scale upgrading of existing communication cables in order to monitor ocean ...
Runlong Zhu   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy