Results 91 to 100 of about 559,327 (258)
Tailoring the Anomalous Hall Effect in van der Waals Ferromagnet Fe3GeTe2
[Purposes] The intrinsic magnetic moments of magnetic materials can lead to anomalous Hall effects, and the Hall resistance can be significantly reduced, thus improving the heat loss in micro- and nanoelectronic devices.
WU Kaile +6 more
doaj +1 more source
Optical fibre nanowire sensors and applications
Optical fibre nanowires (OFN) have recently attracted increased attention because of their numerous applications in sensing and particle manipulation [1] and their extraordinary optical and mechanical properties, which include, amongst others ...
Brambilla, Gilberto, Ding, Ming
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
This paper presents the development and deployment of a multi-point fiber Bragg grating (FBG) sensor system for precise temperature monitoring along the vacuum chamber walls of dipole and Pinger magnets in Indus-2, a synchrotron radiation source.
J. Kumar +8 more
doaj +1 more source
Status of the Fiber Optic Control System Integration (FOCSI) program [PDF]
This report presents a discussion of the progress made in the NASA/NAVY Fiber Optic Control System Integration (FOCSI) program. This program will culminate in open-loop flight tests of passive optical sensors and associated electro-optics on an F-18 ...
Baumbick, Robert J.
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
The deep integration of communication and sensing technology in fiber-optic systems has been highly sought after in recent years, with the aim of rapid and cost-effective large-scale upgrading of existing communication cables in order to monitor ocean ...
Runlong Zhu +9 more
doaj +1 more source

