Results 31 to 40 of about 114,645 (204)

Gamma Ray Burst Prompt Emission Variability in Synchrotron and Synchrotron Self-Compton Lightcurves

, 2012
Gamma Ray Burst prompt emission is believed to originate from electrons accelerated in a highly relativistic outflow. "Internal shocks" due to collisions between shells ejected by the central engine is a leading candidate for electron acceleration. While
Resmi, L., Zhang, B.
core   +1 more source

General Relativistic Radiative Transfer [PDF]

, 2006
We present a general method to calculate radiative transfer including scattering in the continuum as well as in lines in spherically symmetric systems that are influenced by the effects of general relativity (GR).
Baron, E. Baron, Hauschildt, Lindquist, Mihalas, P. H. Hauschildt, S. Knop, Schinder, Zane   +8 more
core   +3 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Single-molecule stochastic resonance

, 2012
Stochastic resonance (SR) is a well known phenomenon in dynamical systems. It consists of the amplification and optimization of the response of a system assisted by stochastic noise.
de Lorenzo, S., Hayashi, K., Huguet, J. M., Manosas, M., Ritort, F.   +4 more
core   +2 more sources

Observation of injection locking in an optomechanical rf oscillator [PDF]

, 2008
Injection locking of a radiation-pressure optomechanical oscillator is demonstrated through external modulation of the optical pump power near the optomechanical oscillation frequency.
Hossein-Zadeh, Mani, Vahala, Kerry J.
core   +1 more source

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

FEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

Análise de Espectro Singular e Wavelet sobre Série Temporal de Profundidade Ótica de Aerossóis no Pantanal do Brasil

Revista Brasileira de Meteorologia
Resumo As variações das propriedades óticas dos aerossóis podem interferir nos processos de transferência de energia entre a atmosfera e a superfície terrestre. A AOD (Aerosol Optical Depth) é a variável mais usada para este propósito, a qual possibilita
Rafael da Silva Palácios, João Basso Marques, Magdiel Josias do Prado, Carlo Ralph De Musis, Fernando da Silva Sallo, Luciana Sanches, Sérgio Roberto de Paulo, José de Souza Nogueira   +7 more
doaj   +1 more source